Zajdel P - Search Results

1

A dual-acting 5-HT₆ receptor inverse agonist/MAO-B inhibitor displays glioprotective and pro-cognitive properties.

Canale V, Grychowska K, Kurczab R, Ryng M, Keeri AR, Satała G, Olejarz-Maciej A, Koczurkiewicz P, Drop M, Blicharz K, Piska K, Pękala E, Janiszewska P, Krawczyk M, Walczak M, Chaumont-Dubel S, Bojarski AJ, Marin P, Popik P, Zajdel P. Canale V, et al. Among authors: zajdel p. Eur J Med Chem. 2020 Dec 15;208:112765. doi: 10.1016/j.ejmech.2020.112765. Epub 2020 Aug 22. Eur J Med Chem. 2020. PMID: 32949963

2

Preliminary study on application of impregnated synthetic peptide TLC stationary phases for the pre-screening of 5-HT1A ligands.

Zajdel P, Bojarski AJ, Byrtus H, Chłoń-Rzepa G, Obniska J, Chevallet P, Martinez J, Pawłowski M. Zajdel P, et al. Biomed Chromatogr. 2003 Jul;17(5):312-7. doi: 10.1002/bmc.224. Biomed Chromatogr. 2003. PMID: 12884396

3

New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.

Jurczyk S, Kołaczkowski M, Maryniak E, Zajdel P, Pawłowski M, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E, Bojarski AJ, Charakchieva-Minol S, Duszyńska B, Nowak G, Maciag D. Jurczyk S, et al. Among authors: zajdel p. J Med Chem. 2004 May 6;47(10):2659-66. doi: 10.1021/jm030946u. J Med Chem. 2004. PMID: 15115407

4

A new class of arylpiperazine derivatives: the library synthesis on SynPhase lanterns and biological evaluation on serotonin 5-HT(1A) and 5-HT(2A) receptors.

Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Pawłowski M, Martinez J. Zajdel P, et al. J Comb Chem. 2004 Sep-Oct;6(5):761-7. doi: 10.1021/cc049970z. J Comb Chem. 2004. PMID: 15360211

5

A study on application of impregnated synthetic peptide TLC stationary phases for the screening of 5-HT1A ligands. Part 2.

Zajdel P, Bojarski AJ, Bugno R, Jurczyk S, Kołaczkowski M, Nowak M, Subra G, Martinez J, Pawłowski M. Zajdel P, et al. Biomed Chromatogr. 2004 Oct;18(8):542-9. doi: 10.1002/bmc.354. Biomed Chromatogr. 2004. PMID: 15386518

6

Parallel solid-phase synthesis and characterization of new sulfonamide and carboxamide proline derivatives as potential CNS agents.

Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Pawłowski M, Martinez J. Zajdel P, et al. Bioorg Med Chem. 2005 Apr 15;13(8):3029-35. doi: 10.1016/j.bmc.2005.01.060. Bioorg Med Chem. 2005. PMID: 15781412

7

Arylpiperazines with N-acylated amino acids as 5-HT1A receptor ligands.

Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Pawłowski M, Martinez J. Zajdel P, et al. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3406-10. doi: 10.1016/j.bmcl.2006.04.035. Epub 2006 May 3. Bioorg Med Chem Lett. 2006. PMID: 16677812

8

Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation.

Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Tatarczyńska E, Nikiforuk A, Chojnacka-Wójcik E, Pawłowski M, Martinez J. Zajdel P, et al. Bioorg Med Chem. 2007 Apr 15;15(8):2907-19. doi: 10.1016/j.bmc.2007.02.018. Epub 2007 Feb 13. Bioorg Med Chem. 2007. PMID: 17321139

9

7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.

Chłoń-Rzepa G, Zmudzki P, Zajdel P, Bojarski AJ, Duszyńska B, Nikiforuk A, Tatarczyńska E, Pawłowski M. Chłoń-Rzepa G, et al. Among authors: zajdel p. Bioorg Med Chem. 2007 Aug 1;15(15):5239-50. doi: 10.1016/j.bmc.2007.05.017. Epub 2007 May 10. Bioorg Med Chem. 2007. PMID: 17517514

10

The influence of an ethylene spacer on the 5-HT(1A) and 5-HT(2A) receptor affinity of arylpiperazine derivatives of amides with N-acylated amino acids and 3-differently substituted pyrrolidine-2,5-diones.

Zajdel P, Subra G, Verdie P, Bojarski AJ, Duszyńska B, Basista K, Obniska J, Martinez J, Pawłowski M. Zajdel P, et al. Eur J Med Chem. 2009 Feb;44(2):800-8. doi: 10.1016/j.ejmech.2008.05.021. Epub 2008 Jul 7. Eur J Med Chem. 2009. PMID: 18603331

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