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Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus.
Perez RK, Gordon MG, Subramaniam M, Kim MC, Hartoularos GC, Targ S, Sun Y, Ogorodnikov A, Bueno R, Lu A, Thompson M, Rappoport N, Dahl A, Lanata CM, Matloubian M, Maliskova L, Kwek SS, Li T, Slyper M, Waldman J, Dionne D, Rozenblatt-Rosen O, Fong L, Dall'Era M, Balliu B, Regev A, Yazdany J, Criswell LA, Zaitlen N, Ye CJ. Perez RK, et al. Among authors: zaitlen n. Science. 2022 Apr 8;376(6589):eabf1970. doi: 10.1126/science.abf1970. Epub 2022 Apr 8. Science. 2022. PMID: 35389781 Free PMC article.
Intersection of population variation and autoimmunity genetics in human T cell activation.
Ye CJ, Feng T, Kwon HK, Raj T, Wilson MT, Asinovski N, McCabe C, Lee MH, Frohlich I, Paik HI, Zaitlen N, Hacohen N, Stranger B, De Jager P, Mathis D, Regev A, Benoist C. Ye CJ, et al. Among authors: zaitlen n. Science. 2014 Sep 12;345(6202):1254665. doi: 10.1126/science.1254665. Science. 2014. PMID: 25214635 Free PMC article.
Transethnic Genetic-Correlation Estimates from Summary Statistics.
Brown BC; Asian Genetic Epidemiology Network Type 2 Diabetes Consortium; Ye CJ, Price AL, Zaitlen N. Brown BC, et al. Among authors: zaitlen n. Am J Hum Genet. 2016 Jul 7;99(1):76-88. doi: 10.1016/j.ajhg.2016.05.001. Epub 2016 Jun 16. Am J Hum Genet. 2016. PMID: 27321947 Free PMC article.
Multiplexed droplet single-cell RNA-sequencing using natural genetic variation.
Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, Ye CJ. Kang HM, et al. Among authors: zaitlen n. Nat Biotechnol. 2018 Jan;36(1):89-94. doi: 10.1038/nbt.4042. Epub 2017 Dec 11. Nat Biotechnol. 2018. PMID: 29227470 Free PMC article.
Genetic and environmental perturbations lead to regulatory decoherence.
Lea A, Subramaniam M, Ko A, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Mononen N, Raitakari OT, Ala-Korpela M, Pajukanta P, Zaitlen N, Ayroles JF. Lea A, et al. Among authors: zaitlen n. Elife. 2019 Mar 5;8:e40538. doi: 10.7554/eLife.40538. Elife. 2019. PMID: 30834892 Free PMC article.
141 results