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Active compounds from a diverse library of triazolothiadiazole and triazolothiadiazine scaffolds: synthesis, crystal structure determination, cytotoxicity, cholinesterase inhibitory activity, and binding mode analysis.
Khan I, Ibrar A, Zaib S, Ahmad S, Furtmann N, Hameed S, Simpson J, Bajorath J, Iqbal J. Khan I, et al. Among authors: zaib s. Bioorg Med Chem. 2014 Nov 1;22(21):6163-73. doi: 10.1016/j.bmc.2014.08.026. Epub 2014 Sep 6. Bioorg Med Chem. 2014. PMID: 25257911
A new entry into the portfolio of α-glucosidase inhibitors as potent therapeutics for type 2 diabetes: Design, bioevaluation and one-pot multi-component synthesis of diamine-bridged coumarinyl oxadiazole conjugates.
Kazmi M, Zaib S, Ibrar A, Amjad ST, Shafique Z, Mehsud S, Saeed A, Iqbal J, Khan I. Kazmi M, et al. Among authors: zaib s. Bioorg Chem. 2018 Apr;77:190-202. doi: 10.1016/j.bioorg.2017.12.022. Epub 2018 Jan 16. Bioorg Chem. 2018. PMID: 29421697
125 results