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The different natural estrogens promote endothelial healing through distinct cell targets.
Davezac M, Zahreddine R, Buscato M, Smirnova NF, Febrissy C, Laurell H, Gilardi-Bresson S, Adlanmerini M, Liere P, Flouriot G, Guennoun R, Laffargue M, Foidart JM, Lenfant F, Arnal JF, Métivier R, Fontaine C. Davezac M, et al. Among authors: zahreddine r. JCI Insight. 2023 Feb 2;8(5):e161284. doi: 10.1172/jci.insight.161284. JCI Insight. 2023. PMID: 36729672 Free PMC article.
Predominant Role of Nuclear Versus Membrane Estrogen Receptor α in Arterial Protection: Implications for Estrogen Receptor α Modulation in Cardiovascular Prevention/Safety.
Guivarc'h E, Buscato M, Guihot AL, Favre J, Vessières E, Grimaud L, Wakim J, Melhem NJ, Zahreddine R, Adlanmerini M, Loufrani L, Knauf C, Katzenellenbogen JA, Katzenellenbogen BS, Foidart JM, Gourdy P, Lenfant F, Arnal JF, Henrion D, Fontaine C. Guivarc'h E, et al. Among authors: zahreddine r. J Am Heart Assoc. 2018 Jun 29;7(13):e008950. doi: 10.1161/JAHA.118.008950. J Am Heart Assoc. 2018. PMID: 29959137 Free PMC article.
Selective Liver Estrogen Receptor α Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice.
Guillaume M, Riant E, Fabre A, Raymond-Letron I, Buscato M, Davezac M, Tramunt B, Montagner A, Smati S, Zahreddine R, Palierne G, Valera MC, Guillou H, Lenfant F, Unsicker K, Metivier R, Fontaine C, Arnal JF, Gourdy P. Guillaume M, et al. Among authors: zahreddine r. Hepatol Commun. 2019 Apr 29;3(7):908-924. doi: 10.1002/hep4.1363. eCollection 2019 Jul. Hepatol Commun. 2019. PMID: 31304450 Free PMC article.
The Impact of Estrogen Receptor in Arterial and Lymphatic Vascular Diseases.
Fontaine C, Morfoisse F, Tatin F, Zamora A, Zahreddine R, Henrion D, Arnal JF, Lenfant F, Garmy-Susini B. Fontaine C, et al. Among authors: zahreddine r. Int J Mol Sci. 2020 May 4;21(9):3244. doi: 10.3390/ijms21093244. Int J Mol Sci. 2020. PMID: 32375307 Free PMC article. Review.
Mutation of Arginine 264 on ERα (Estrogen Receptor Alpha) Selectively Abrogates the Rapid Signaling of Estradiol in the Endothelium Without Altering Fertility.
Adlanmerini M, Fébrissy C, Zahreddine R, Vessières E, Buscato M, Solinhac R, Favre J, Anquetil T, Guihot AL, Boudou F, Raymond-Letron I, Chambon P, Gourdy P, Ohlsson C, Laurell H, Fontaine C, Metivier R, Le Romancer M, Henrion D, Arnal JF, Lenfant F. Adlanmerini M, et al. Among authors: zahreddine r. Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):2143-2158. doi: 10.1161/ATVBAHA.120.314159. Epub 2020 Jul 9. Arterioscler Thromb Vasc Biol. 2020. PMID: 32640903 Free article.
Tamoxifen Accelerates Endothelial Healing by Targeting ERα in Smooth Muscle Cells.
Zahreddine R, Davezac M, Smirnova N, Buscato M, Lhuillier E, Lupieri A, Solinhac R, Vinel A, Vessieres E, Henrion D, Renault MA, Gadeau AP, Flouriot G, Lenfant F, Laffargue M, Métivier R, Arnal JF, Fontaine C. Zahreddine R, et al. Circ Res. 2020 Dec 4;127(12):1473-1487. doi: 10.1161/CIRCRESAHA.120.317062. Epub 2020 Oct 5. Circ Res. 2020. PMID: 33012251 Free article.
Estetrol prevents Western diet-induced obesity and atheroma independently of hepatic estrogen receptor α.
Buscato M, Davezac M, Zahreddine R, Adlanmerini M, Métivier R, Fillet M, Cobraiville G, Moro C, Foidart JM, Lenfant F, Gourdy P, Arnal JF, Fontaine C. Buscato M, et al. Among authors: zahreddine r. Am J Physiol Endocrinol Metab. 2021 Jan 1;320(1):E19-E29. doi: 10.1152/ajpendo.00211.2020. Epub 2020 Nov 2. Am J Physiol Endocrinol Metab. 2021. PMID: 33135461 Free article.
Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner.
Favre J, Vessieres E, Guihot AL, Proux C, Grimaud L, Rivron J, Garcia MC, Réthoré L, Zahreddine R, Davezac M, Fébrissy C, Adlanmerini M, Loufrani L, Procaccio V, Foidart JM, Flouriot G, Lenfant F, Fontaine C, Arnal JF, Henrion D. Favre J, et al. Among authors: zahreddine r. Elife. 2021 Nov 29;10:e68695. doi: 10.7554/eLife.68695. Elife. 2021. PMID: 34842136 Free PMC article.
Estrogen Receptor and Vascular Aging.
Davezac M, Buscato M, Zahreddine R, Lacolley P, Henrion D, Lenfant F, Arnal JF, Fontaine C. Davezac M, et al. Among authors: zahreddine r. Front Aging. 2021 Sep 24;2:727380. doi: 10.3389/fragi.2021.727380. eCollection 2021. Front Aging. 2021. PMID: 35821994 Free PMC article. Review.
17 results