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Impaired neuron differentiation in GBA-associated Parkinson's disease is linked to cell cycle defects in organoids.
NPJ Parkinsons Dis. 2023 Dec 18;9(1):166. doi: 10.1038/s41531-023-00616-8.
NPJ Parkinsons Dis. 2023.
PMID: 38110400
Free PMC article.
Omics data integration suggests a potential idiopathic Parkinson's disease signature.
Zagare A, Preciat G, Nickels SL, Luo X, Monzel AS, Gomez-Giro G, Robertson G, Jaeger C, Sharif J, Koseki H, Diederich NJ, Glaab E, Fleming RMT, Schwamborn JC.
Zagare A, et al.
Commun Biol. 2023 Nov 20;6(1):1179. doi: 10.1038/s42003-023-05548-w.
Commun Biol. 2023.
PMID: 37985891
Free PMC article.
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Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression.
Zagare A, Barmpa K, Smajic S, Smits LM, Grzyb K, Grünewald A, Skupin A, Nickels SL, Schwamborn JC.
Zagare A, et al.
Am J Hum Genet. 2022 Feb 3;109(2):311-327. doi: 10.1016/j.ajhg.2021.12.009. Epub 2022 Jan 24.
Am J Hum Genet. 2022.
PMID: 35077669
Free PMC article.
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A robust protocol for the generation of human midbrain organoids.
Zagare A, Gobin M, Monzel AS, Schwamborn JC.
Zagare A, et al.
STAR Protoc. 2021 May 4;2(2):100524. doi: 10.1016/j.xpro.2021.100524. eCollection 2021 Jun 18.
STAR Protoc. 2021.
PMID: 34027482
Free PMC article.
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Machine learning-assisted neurotoxicity prediction in human midbrain organoids.
Monzel AS, Hemmer K, Kaoma T, Smits LM, Bolognin S, Lucarelli P, Rosety I, Zagare A, Antony P, Nickels SL, Krueger R, Azuaje F, Schwamborn JC.
Monzel AS, et al. Among authors: zagare a.
Parkinsonism Relat Disord. 2020 Jun;75:105-109. doi: 10.1016/j.parkreldis.2020.05.011. Epub 2020 May 8.
Parkinsonism Relat Disord. 2020.
PMID: 32534431
Free article.
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Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0.
Heirendt L, Arreckx S, Pfau T, Mendoza SN, Richelle A, Heinken A, Haraldsdóttir HS, Wachowiak J, Keating SM, Vlasov V, Magnusdóttir S, Ng CY, Preciat G, Žagare A, Chan SHJ, Aurich MK, Clancy CM, Modamio J, Sauls JT, Noronha A, Bordbar A, Cousins B, El Assal DC, Valcarcel LV, Apaolaza I, Ghaderi S, Ahookhosh M, Ben Guebila M, Kostromins A, Sompairac N, Le HM, Ma D, Sun Y, Wang L, Yurkovich JT, Oliveira MAP, Vuong PT, El Assal LP, Kuperstein I, Zinovyev A, Hinton HS, Bryant WA, Aragón Artacho FJ, Planes FJ, Stalidzans E, Maass A, Vempala S, Hucka M, Saunders MA, Maranas CD, Lewis NE, Sauter T, Palsson BØ, Thiele I, Fleming RMT.
Heirendt L, et al. Among authors: zagare a.
Nat Protoc. 2019 Mar;14(3):639-702. doi: 10.1038/s41596-018-0098-2.
Nat Protoc. 2019.
PMID: 30787451
Free PMC article.
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The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease.
Noronha A, Modamio J, Jarosz Y, Guerard E, Sompairac N, Preciat G, Daníelsdóttir AD, Krecke M, Merten D, Haraldsdóttir HS, Heinken A, Heirendt L, Magnúsdóttir S, Ravcheev DA, Sahoo S, Gawron P, Friscioni L, Garcia B, Prendergast M, Puente A, Rodrigues M, Roy A, Rouquaya M, Wiltgen L, Žagare A, John E, Krueger M, Kuperstein I, Zinovyev A, Schneider R, Fleming RMT, Thiele I.
Noronha A, et al. Among authors: zagare a.
Nucleic Acids Res. 2019 Jan 8;47(D1):D614-D624. doi: 10.1093/nar/gky992.
Nucleic Acids Res. 2019.
PMID: 30371894
Free PMC article.
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