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Preclinical evaluation of 1,2,4-triazole-based compounds targeting voltage-gated sodium channels (VGSCs) as promising anticonvulsant drug candidates.
Kaproń B, Łuszczki JJ, Siwek A, Karcz T, Nowak G, Zagaja M, Andres-Mach M, Stasiłowicz A, Cielecka-Piontek J, Kocki J, Plech T. Kaproń B, et al. Among authors: zagaja m. Bioorg Chem. 2020 Jan;94:103355. doi: 10.1016/j.bioorg.2019.103355. Epub 2019 Oct 17. Bioorg Chem. 2020. PMID: 31662213 Free article.
Effects of WIN 55,212-2 (a synthetic cannabinoid CB1 and CB2 receptor agonist) on the anticonvulsant activity of various novel antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice.
Florek-Luszczki M, Wlaz A, Zagaja M, Andres-Mach M, Kondrat-Wrobel MW, Luszczki JJ. Florek-Luszczki M, et al. Among authors: zagaja m. Pharmacol Biochem Behav. 2015 Mar;130:53-8. doi: 10.1016/j.pbb.2015.01.003. Epub 2015 Jan 13. Pharmacol Biochem Behav. 2015. PMID: 25592741
Influence of arachidonyl-2'-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the anticonvulsant and acute side-effect potentials of clobazam, lacosamide, and pregabalin in the maximal electroshock-induced seizure model and chimney test in mice.
Florek-Luszczki M, Zagaja M, Luszczki JJ. Florek-Luszczki M, et al. Among authors: zagaja m. Fundam Clin Pharmacol. 2015 Aug;29(4):382-93. doi: 10.1111/fcp.12123. Epub 2015 May 12. Fundam Clin Pharmacol. 2015. PMID: 25904357
49 results