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Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione derivatives as 5-HT1A receptor partial agonists.
Partyka A, Zagórska A, Kotańska M, Walczak M, Jastrzębska-Więsek M, Knutelska J, Bednarski M, Głuch-Lutwin M, Mordyl B, Janiszewska P, Wesołowska A. Partyka A, et al. Among authors: zagorska a. PLoS One. 2020 Aug 7;15(8):e0237196. doi: 10.1371/journal.pone.0237196. eCollection 2020. PLoS One. 2020. PMID: 32764777 Free PMC article.
New arylpiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and dihydro[1,3]oxazolo[2,3-f]purinedione targeting the serotonin 5-HT1A /5-HT2A /5-HT7 and dopamine D2 receptors.
Chłoń-Rzepa G, Zagórska A, Bucki A, Kołaczkowski M, Pawłowski M, Satała G, Bojarski AJ, Partyka A, Wesołowska A, Pękala E, Słoczyńska K. Chłoń-Rzepa G, et al. Among authors: zagorska a. Arch Pharm (Weinheim). 2015 Apr;348(4):242-53. doi: 10.1002/ardp.201500015. Epub 2015 Mar 13. Arch Pharm (Weinheim). 2015. PMID: 25773907
Synthesis and biological evaluation of 2-fluoro and 3-trifluoromethyl-phenyl-piperazinylalkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione as potential antidepressant agents.
Zagórska A, Bucki A, Kołaczkowski M, Siwek A, Głuch-Lutwin M, Starowicz G, Kazek G, Partyka A, Wesołowska A, Słoczyńska K, Pękala E, Pawłowski M. Zagórska A, et al. J Enzyme Inhib Med Chem. 2016;31(sup3):10-24. doi: 10.1080/14756366.2016.1198902. Epub 2016 Jun 29. J Enzyme Inhib Med Chem. 2016. PMID: 27353547
87 results