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Use of transcriptomics in understanding mechanisms of drug-induced toxicity.
Pharmacogenomics. 2010 Apr;11(4):573-85. doi: 10.2217/pgs.10.37.
Pharmacogenomics. 2010.
PMID: 20350139
Free PMC article.
Review.
Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation.
Fannin RD, Russo M, O'Connell TM, Gerrish K, Winnike JH, Macdonald J, Newton J, Malik S, Sieber SO, Parker J, Shah R, Zhou T, Watkins PB, Paules RS.
Fannin RD, et al.
Hepatology. 2010 Jan;51(1):227-36. doi: 10.1002/hep.23330.
Hepatology. 2010.
PMID: 19918972
Free PMC article.
Clinical Trial.
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