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Page 1
A binding kinetics study of human adenosine A3 receptor agonists.
Xia L, Kyrizaki A, Tosh DK, van Duijl TT, Roorda JC, Jacobson KA, IJzerman AP, Heitman LH. Xia L, et al. Biochem Pharmacol. 2018 Jul;153:248-259. doi: 10.1016/j.bcp.2017.12.026. Epub 2018 Jan 3. Biochem Pharmacol. 2018. PMID: 29305857 Free PMC article.
Exploring the Role of N6-Substituents in Potent Dual Acting 5'-C-Ethyltetrazolyladenosine Derivatives: Synthesis, Binding, Functional Assays, and Antinociceptive Effects in Mice ∇.
Petrelli R, Scortichini M, Kachler S, Boccella S, Cerchia C, Torquati I, Del Bello F, Salvemini D, Novellino E, Luongo L, Maione S, Jacobson KA, Lavecchia A, Klotz KN, Cappellacci L. Petrelli R, et al. J Med Chem. 2017 May 25;60(10):4327-4341. doi: 10.1021/acs.jmedchem.7b00291. Epub 2017 May 5. J Med Chem. 2017. PMID: 28447789 Free PMC article.
N6-Substituted 5'-N-Methylcarbamoyl-4'-selenoadenosines as Potent and Selective A3 Adenosine Receptor Agonists with Unusual Sugar Puckering and Nucleobase Orientation.
Yu J, Zhao LX, Park J, Lee HW, Sahu PK, Cui M, Moss SM, Hammes E, Warnick E, Gao ZG, Noh M, Choi S, Ahn HC, Choi J, Jacobson KA, Jeong LS. Yu J, et al. J Med Chem. 2017 Apr 27;60(8):3422-3437. doi: 10.1021/acs.jmedchem.7b00241. Epub 2017 Apr 19. J Med Chem. 2017. PMID: 28380296 Free PMC article.
Ocular Purine Receptors as Drug Targets in the Eye.
Jacobson KA, Civan MM. Jacobson KA, et al. J Ocul Pharmacol Ther. 2016 Oct;32(8):534-547. doi: 10.1089/jop.2016.0090. Epub 2016 Aug 30. J Ocul Pharmacol Ther. 2016. PMID: 27574786 Free PMC article. Review.