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Structural Optimization and Anticancer Activity of Polo-like Kinase 1 (Plk1) Polo-Box Domain (PBD) Inhibitors and Their Prodrugs.
Park JE, Lee H, Oliva P, Kirsch K, Kim B, Ahn JI, Alverez CN, Gaikwad S, Krausz KW, O'Connor R, Rai G, Simeonov A, Mock BA, Gonzalez FJ, Lee KS, Jacobson KA. Park JE, et al. ACS Pharmacol Transl Sci. 2023 Feb 20;6(3):422-446. doi: 10.1021/acsptsci.2c00250. eCollection 2023 Mar 10. ACS Pharmacol Transl Sci. 2023. PMID: 36926457 Free PMC article.
Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation.
Lu D, Liu Y, Luo Y, Zhao J, Feng C, Xue L, Xu J, Wang Q, Yan T, Xiao P, Krausz KW, Gonzalez FJ, Xie C. Lu D, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Feb;1867(2):159089. doi: 10.1016/j.bbalip.2021.159089. Epub 2021 Nov 29. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 34856412 Free PMC article.
Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1.
Ramdhan DH, Kamijima M, Yamada N, Ito Y, Yanagiba Y, Nakamura D, Okamura A, Ichihara G, Aoyama T, Gonzalez FJ, Nakajima T. Ramdhan DH, et al. Toxicol Appl Pharmacol. 2008 Sep 15;231(3):300-7. doi: 10.1016/j.taap.2008.04.020. Epub 2008 May 2. Toxicol Appl Pharmacol. 2008. PMID: 18565563 Free PMC article.