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Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG|GTG) increases binding of the Tcf3|Ascl1 helix-loop-helix heterodimer 10-fold.
Biochem Biophys Res Commun. 2014 Jun 27;449(2):248-55. doi: 10.1016/j.bbrc.2014.05.018. Epub 2014 May 14.
Biochem Biophys Res Commun. 2014.
PMID: 24835951
Free PMC article.
CG methylation.
Vinson C, Chatterjee R.
Vinson C, et al.
Epigenomics. 2012 Dec;4(6):655-63. doi: 10.2217/epi.12.55.
Epigenomics. 2012.
PMID: 23244310
Free PMC article.
Review.
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