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Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling.
Zhang X, Evans TD, Chen S, Sergin I, Stitham J, Jeong SJ, Rodriguez-Velez A, Yeh YS, Park A, Jung IH, Diwan A, Schilling JD, Rom O, Yurdagul A, Epelman S, Cho J, Lodhi IJ, Mittendorfer B, Razani B. Zhang X, et al. Among authors: yurdagul a. Circ Res. 2023 Jul 21;133(3):200-219. doi: 10.1161/CIRCRESAHA.122.321542. Epub 2023 Jun 23. Circ Res. 2023. PMID: 37350264
EphA2 Expression Regulates Inflammation and Fibroproliferative Remodeling in Atherosclerosis.
Finney AC, Funk SD, Green JM, Yurdagul A Jr, Rana MA, Pistorius R, Henry M, Yurochko A, Pattillo CB, Traylor JG, Chen J, Woolard MD, Kevil CG, Orr AW. Finney AC, et al. Among authors: yurdagul a jr. Circulation. 2017 Aug 8;136(6):566-582. doi: 10.1161/CIRCULATIONAHA.116.026644. Epub 2017 May 9. Circulation. 2017. PMID: 28487392 Free PMC article.
Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis.
Liu Y, Zhao Y, Shukha Y, Lu H, Wang L, Liu Z, Liu C, Zhao Y, Wang H, Zhao G, Liang W, Fan Y, Chang L, Yurdagul A Jr, Pattillo CB, Orr AW, Aviram M, Wen B, Garcia-Barrio MT, Zhang J, Liu W, Sun D, Hayek T, Chen YE, Rom O. Liu Y, et al. Among authors: yurdagul a jr. Cell Rep. 2021 Jul 27;36(4):109420. doi: 10.1016/j.celrep.2021.109420. Cell Rep. 2021. PMID: 34320345 Free PMC article.
Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis.
Rom O, Liu Y, Finney AC, Ghrayeb A, Zhao Y, Shukha Y, Wang L, Rajanayake KK, Das S, Rashdan NA, Weissman N, Delgadillo L, Wen B, Garcia-Barrio MT, Aviram M, Kevil CG, Yurdagul A Jr, Pattillo CB, Zhang J, Sun D, Hayek T, Gottlieb E, Mor I, Chen YE. Rom O, et al. Among authors: yurdagul a jr. Redox Biol. 2022 Jun;52:102313. doi: 10.1016/j.redox.2022.102313. Epub 2022 Apr 13. Redox Biol. 2022. PMID: 35447412 Free PMC article.
SLAMF1 is expressed and secreted by hepatocytes and the liver in nonalcoholic fatty liver disease.
Gomez-Torres O, Amatya S, Kamberov L, Dhaibar HA, Khanna P, Rom O, Yurdagul A Jr, Orr AW, Nunez K, Thevenot P, Cohen A, Samant H, Alexander JS, Burgos-Ramos E, Chapa-Rodriguez A, Cruz-Topete D. Gomez-Torres O, et al. Among authors: yurdagul a jr. Am J Physiol Gastrointest Liver Physiol. 2022 Sep 1;323(3):G177-G187. doi: 10.1152/ajpgi.00289.2021. Epub 2022 Jul 19. Am J Physiol Gastrointest Liver Physiol. 2022. PMID: 35853010 Free PMC article.
Spatially Resolved Metabolites in Stable and Unstable Human Atherosclerotic Plaques Identified by Mass Spectrometry Imaging.
Seeley EH, Liu Z, Yuan S, Stroope C, Cockerham E, Rashdan NA, Delgadillo LF, Finney AC, Kumar D, Das S, Razani B, Liu W, Traylor J, Orr AW, Rom O, Pattillo CB, Yurdagul A Jr. Seeley EH, et al. Among authors: yurdagul a jr. Arterioscler Thromb Vasc Biol. 2023 Sep;43(9):1626-1635. doi: 10.1161/ATVBAHA.122.318684. Epub 2023 Jun 29. Arterioscler Thromb Vasc Biol. 2023. PMID: 37381983 Free article.
Amino Acid Metabolism and Atherosclerotic Cardiovascular Disease.
Anand SK, Governale TA, Zhang X, Razani B, Yurdagul A Jr, Pattillo CB, Rom O. Anand SK, et al. Among authors: yurdagul a jr. Am J Pathol. 2024 Apr;194(4):510-524. doi: 10.1016/j.ajpath.2023.12.006. Epub 2024 Jan 1. Am J Pathol. 2024. PMID: 38171450 Review.
Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk.
Zhang X, Kapoor D, Jeong SJ, Fappi A, Stitham J, Shabrish V, Sergin I, Yousif E, Rodriguez-Velez A, Yeh YS, Park A, Yurdagul A Jr, Rom O, Epelman S, Schilling JD, Sardiello M, Diwan A, Cho J, Stitziel NO, Javaheri A, Lodhi IJ, Mittendorfer B, Razani B. Zhang X, et al. Among authors: yurdagul a jr. Nat Metab. 2024 Feb;6(2):359-377. doi: 10.1038/s42255-024-00984-2. Epub 2024 Feb 19. Nat Metab. 2024. PMID: 38409323
49 results