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Wnt7a deficit is associated with dysfunctional angiogenesis in pulmonary arterial hypertension.
Chakraborty A, Nathan A, Orcholski M, Agarwal S, Shamskhou EA, Auer N, Mitra A, Guardado ES, Swaminathan G, Condon DF, Yu J, McCarra M, Juul NH, Mallory A, Guzman-Hernandez RA, Yuan K, Rojas V, Crossno JT, Yung LM, Yu PB, Spencer T, Winn RA, Frump A, Karoor V, Lahm T, Hedlin H, Fineman JR, Lafyatis R, Knutsen CNF, Alvira CM, Cornfield DN, de Jesus Perez VA. Chakraborty A, et al. Among authors: yung lm. Eur Respir J. 2023 Jun 8;61(6):2201625. doi: 10.1183/13993003.01625-2022. Print 2023 Jun. Eur Respir J. 2023. PMID: 37024132 Free PMC article.
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells.
Szulcek R, Sanchez-Duffhues G, Rol N, Pan X, Tsonaka R, Dickhoff C, Yung LM, Manz XD, Kurakula K, Kiełbasa SM, Mei H, Timens W, Yu PB, Bogaard HJ, Goumans MJ. Szulcek R, et al. Among authors: yung lm. Angiogenesis. 2020 Nov;23(4):699-714. doi: 10.1007/s10456-020-09741-x. Epub 2020 Aug 19. Angiogenesis. 2020. PMID: 32813135 Free PMC article.
ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension.
Yung LM, Yang P, Joshi S, Augur ZM, Kim SSJ, Bocobo GA, Dinter T, Troncone L, Chen PS, McNeil ME, Southwood M, Poli de Frias S, Knopf J, Rosas IO, Sako D, Pearsall RS, Quisel JD, Li G, Kumar R, Yu PB. Yung LM, et al. Sci Transl Med. 2020 May 13;12(543):eaaz5660. doi: 10.1126/scitranslmed.aaz5660. Sci Transl Med. 2020. PMID: 32404506 Free PMC article.
Room With a View.
Yung LM, Yu PB. Yung LM, et al. Circ Cardiovasc Imaging. 2018 Aug;11(8):e008148. doi: 10.1161/CIRCIMAGING.118.008148. Circ Cardiovasc Imaging. 2018. PMID: 30354505 Free PMC article. No abstract available.
Bone Morphogenetic Protein 9 Is a Mechanistic Biomarker of Portopulmonary Hypertension.
Nikolic I, Yung LM, Yang P, Malhotra R, Paskin-Flerlage SD, Dinter T, Bocobo GA, Tumelty KE, Faugno AJ, Troncone L, McNeil ME, Huang X, Coser KR, Lai CSC, Upton PD, Goumans MJ, Zamanian RT, Elliott CG, Lee A, Zheng W, Berasi SP, Huard C, Morrell NW, Chung RT, Channick RW, Roberts KE, Yu PB. Nikolic I, et al. Among authors: yung lm. Am J Respir Crit Care Med. 2019 Apr 1;199(7):891-902. doi: 10.1164/rccm.201807-1236OC. Am J Respir Crit Care Med. 2019. PMID: 30312106 Free PMC article.
NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension.
Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, Oldham WM, Khanna D, Graham BB, Seo S, Gladyshev VN, Yu PB, Fredenburgh LE, Loscalzo J, Leopold JA, Maron BA. Samokhin AO, et al. Among authors: yung lm. Sci Transl Med. 2018 Jun 13;10(445):eaap7294. doi: 10.1126/scitranslmed.aap7294. Sci Transl Med. 2018. PMID: 29899023 Free PMC article.
Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension.
Aghamohammadzadeh R, Zhang YY, Stephens TE, Arons E, Zaman P, Polach KJ, Matar M, Yung LM, Yu PB, Bowman FP, Opotowsky AR, Waxman AB, Loscalzo J, Leopold JA, Maron BA. Aghamohammadzadeh R, et al. Among authors: yung lm. FASEB J. 2016 Jul;30(7):2511-27. doi: 10.1096/fj.201500042. Epub 2016 Mar 22. FASEB J. 2016. PMID: 27006450 Free PMC article.
34 results