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Structural Basis of Colchicine-Site targeting Acylhydrazones active against Multidrug-Resistant Acute Lymphoblastic Leukemia.
Cury NM, Mühlethaler T, Laranjeira ABA, Canevarolo RR, Zenatti PP, Lucena-Agell D, Barasoain I, Song C, Sun D, Dovat S, Yunes RA, Prota AE, Steinmetz MO, Díaz JF, Yunes JA. Cury NM, et al. Among authors: yunes ja, yunes ra. iScience. 2019 Nov 22;21:95-109. doi: 10.1016/j.isci.2019.10.003. Epub 2019 Oct 2. iScience. 2019. PMID: 31655259 Free PMC article.
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.
Zenatti PP, Ribeiro D, Li W, Zuurbier L, Silva MC, Paganin M, Tritapoe J, Hixon JA, Silveira AB, Cardoso BA, Sarmento LM, Correia N, Toribio ML, Kobarg J, Horstmann M, Pieters R, Brandalise SR, Ferrando AA, Meijerink JP, Durum SK, Yunes JA, Barata JT. Zenatti PP, et al. Among authors: yunes ja. Nat Genet. 2011 Sep 4;43(10):932-9. doi: 10.1038/ng.924. Nat Genet. 2011. PMID: 21892159 Free PMC article.
Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors.
Salum LB, Altei WF, Chiaradia LD, Cordeiro MN, Canevarolo RR, Melo CP, Winter E, Mattei B, Daghestani HN, Santos-Silva MC, Creczynski-Pasa TB, Yunes RA, Yunes JA, Andricopulo AD, Day BW, Nunes RJ, Vogt A. Salum LB, et al. Among authors: yunes ja, yunes ra. Eur J Med Chem. 2013 May;63:501-10. doi: 10.1016/j.ejmech.2013.02.037. Epub 2013 Mar 6. Eur J Med Chem. 2013. PMID: 23524161 Free PMC article.
N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia.
Salum LB, Mascarello A, Canevarolo RR, Altei WF, Laranjeira AB, Neuenfeldt PD, Stumpf TR, Chiaradia-Delatorre LD, Vollmer LL, Daghestani HN, de Souza Melo CP, Silveira AB, Leal PC, Frederico MJ, do Nascimento LF, Santos AR, Andricopulo AD, Day BW, Yunes RA, Vogt A, Yunes JA, Nunes RJ. Salum LB, et al. Among authors: yunes ja, yunes ra. Eur J Med Chem. 2015;96:504-18. doi: 10.1016/j.ejmech.2015.02.041. Epub 2015 Feb 23. Eur J Med Chem. 2015. PMID: 25951294
Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340).
Siqueira RP, Barbosa Éde A, Polêto MD, Righetto GL, Seraphim TV, Salgado RL, Ferreira JG, Barros MV, de Oliveira LL, Laranjeira AB, Almeida MR, Júnior AS, Fietto JL, Kobarg J, de Oliveira EB, Teixeira RR, Borges JC, Yunes JA, Bressan GC. Siqueira RP, et al. Among authors: yunes ja. PLoS One. 2015 Aug 5;10(8):e0134882. doi: 10.1371/journal.pone.0134882. eCollection 2015. PLoS One. 2015. PMID: 26244849 Free PMC article.
SB225002 Induces Cell Death and Cell Cycle Arrest in Acute Lymphoblastic Leukemia Cells through the Activation of GLIPR1.
de Vasconcellos JF, Laranjeira AB, Leal PC, Bhasin MK, Zenatti PP, Nunes RJ, Yunes RA, Nowill AE, Libermann TA, Zerbini LF, Yunes JA. de Vasconcellos JF, et al. Among authors: yunes ja, yunes ra. PLoS One. 2015 Aug 24;10(8):e0134783. doi: 10.1371/journal.pone.0134783. eCollection 2015. PLoS One. 2015. PMID: 26302043 Free PMC article.
135 results