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Gut microbial carbohydrate metabolism contributes to insulin resistance.
Takeuchi T, Kubota T, Nakanishi Y, Tsugawa H, Suda W, Kwon AT, Yazaki J, Ikeda K, Nemoto S, Mochizuki Y, Kitami T, Yugi K, Mizuno Y, Yamamichi N, Yamazaki T, Takamoto I, Kubota N, Kadowaki T, Arner E, Carninci P, Ohara O, Arita M, Hattori M, Koyasu S, Ohno H. Takeuchi T, et al. Among authors: yugi k. Nature. 2023 Sep;621(7978):389-395. doi: 10.1038/s41586-023-06466-x. Epub 2023 Aug 30. Nature. 2023. PMID: 37648852 Free PMC article.
Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity.
Kokaji T, Hatano A, Ito Y, Yugi K, Eto M, Morita K, Ohno S, Fujii M, Hironaka KI, Egami R, Terakawa A, Tsuchiya T, Ozaki H, Inoue H, Uda S, Kubota H, Suzuki Y, Ikeda K, Arita M, Matsumoto M, Nakayama KI, Hirayama A, Soga T, Kuroda S. Kokaji T, et al. Among authors: yugi k. Sci Signal. 2020 Dec 1;13(660):eaaz1236. doi: 10.1126/scisignal.aaz1236. Sci Signal. 2020. PMID: 33262292
Reconstruction of insulin signal flow from phosphoproteome and metabolome data.
Yugi K, Kubota H, Toyoshima Y, Noguchi R, Kawata K, Komori Y, Uda S, Kunida K, Tomizawa Y, Funato Y, Miki H, Matsumoto M, Nakayama KI, Kashikura K, Endo K, Ikeda K, Soga T, Kuroda S. Yugi K, et al. Cell Rep. 2014 Aug 21;8(4):1171-83. doi: 10.1016/j.celrep.2014.07.021. Epub 2014 Aug 14. Cell Rep. 2014. PMID: 25131207 Free article.
Metabolism-Centric Trans-Omics.
Yugi K, Kuroda S. Yugi K, et al. Cell Syst. 2017 Jan 25;4(1):19-20. doi: 10.1016/j.cels.2017.01.007. Cell Syst. 2017. PMID: 28125790 Free article.
In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states.
Kokaji T, Eto M, Hatano A, Yugi K, Morita K, Ohno S, Fujii M, Hironaka KI, Ito Y, Egami R, Uematsu S, Terakawa A, Pan Y, Maehara H, Li D, Bai Y, Tsuchiya T, Ozaki H, Inoue H, Kubota H, Suzuki Y, Hirayama A, Soga T, Kuroda S. Kokaji T, et al. Among authors: yugi k. Sci Rep. 2022 Aug 12;12(1):13719. doi: 10.1038/s41598-022-17964-9. Sci Rep. 2022. PMID: 35962137 Free PMC article.
Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism.
Krycer JR, Yugi K, Hirayama A, Fazakerley DJ, Quek LE, Scalzo R, Ohno S, Hodson MP, Ikeda S, Shoji F, Suzuki K, Domanova W, Parker BL, Nelson ME, Humphrey SJ, Turner N, Hoehn KL, Cooney GJ, Soga T, Kuroda S, James DE. Krycer JR, et al. Among authors: yugi k. Cell Rep. 2017 Dec 19;21(12):3536-3547. doi: 10.1016/j.celrep.2017.11.085. Cell Rep. 2017. PMID: 29262332 Free article.
32 results