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The evolution and clinical impact of hepatitis B virus genome diversity.
Revill PA, Tu T, Netter HJ, Yuen LKW, Locarnini SA, Littlejohn M. Revill PA, et al. Among authors: yuen lkw. Nat Rev Gastroenterol Hepatol. 2020 Oct;17(10):618-634. doi: 10.1038/s41575-020-0296-6. Epub 2020 May 28. Nat Rev Gastroenterol Hepatol. 2020. PMID: 32467580 Review.
Origins and Evolution of the Primate Hepatitis B Virus.
Locarnini SA, Littlejohn M, Yuen LKW. Locarnini SA, et al. Among authors: yuen lkw. Front Microbiol. 2021 May 24;12:653684. doi: 10.3389/fmicb.2021.653684. eCollection 2021. Front Microbiol. 2021. PMID: 34108947 Free PMC article. Review.
Defective hepatitis B virus DNA is not associated with disease status but is reduced by polymerase mutations associated with drug resistance.
Preiss S, Littlejohn M, Angus P, Thompson A, Desmond P, Lewin SR, Sasadeusz J, Matthews G, Dore GJ, Shaw T, Sozzi V, Yuen L, Lau G, Ayres A, Thio C, Avihingsanon A, Ruxrungtham K, Locarnini S, Revill PA. Preiss S, et al. Hepatology. 2008 Sep;48(3):741-9. doi: 10.1002/hep.22386. Hepatology. 2008. PMID: 18571815 Free PMC article.
Possible origins and evolution of the hepatitis B virus (HBV).
Locarnini S, Littlejohn M, Aziz MN, Yuen L. Locarnini S, et al. Semin Cancer Biol. 2013 Dec;23(6 Pt B):561-75. doi: 10.1016/j.semcancer.2013.08.006. Epub 2013 Sep 3. Semin Cancer Biol. 2013. PMID: 24013024 Review.
Deep sequencing shows that HBV basal core promoter and precore variants reduce the likelihood of HBsAg loss following tenofovir disoproxil fumarate therapy in HBeAg-positive chronic hepatitis B.
Bayliss J, Yuen L, Rosenberg G, Wong D, Littlejohn M, Jackson K, Gaggar A, Kitrinos KM, Subramanian GM, Marcellin P, Buti M, Janssen HLA, Gane E, Sozzi V, Colledge D, Hammond R, Edwards R, Locarnini S, Thompson A, Revill PA. Bayliss J, et al. Gut. 2017 Nov;66(11):2013-2023. doi: 10.1136/gutjnl-2015-309300. Epub 2016 Aug 17. Gut. 2017. PMID: 27534671 Clinical Trial.
77 results