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MLH1-methylated endometrial cancer under 60 years of age as the "sentinel" cancer in female carriers of high-risk constitutional MLH1 epimutation.
Hitchins MP, Alvarez R, Zhou L, Aguirre F, Dámaso E, Pineda M, Capella G, Wong JJ, Yuan X, Ryan SR, Sathe DS, Baxter MD, Cannon T, Biswas R, DeMarco T, Grzelak D, Hampel H, Pearlman R. Hitchins MP, et al. Among authors: yuan x. Gynecol Oncol. 2023 Apr;171:129-140. doi: 10.1016/j.ygyno.2023.02.017. Epub 2023 Mar 8. Gynecol Oncol. 2023. PMID: 36893489 Free PMC article.
Methylated SEPTIN9 plasma test for colorectal cancer detection may be applicable to Lynch syndrome.
Hitchins MP, Vogelaar IP, Brennan K, Haraldsdottir S, Zhou N, Martin B, Alvarez R, Yuan X, Kim S, Guindi M, Hendifar AE, Kalady MF, DeVecchio J, Church JM, de la Chapelle A, Hampel H, Pearlman R, Christensen M, Snyder C, Lanspa SJ, Haile RW, Lynch HT. Hitchins MP, et al. Among authors: yuan x. BMJ Open Gastroenterol. 2019 May 28;6(1):e000299. doi: 10.1136/bmjgast-2019-000299. eCollection 2019. BMJ Open Gastroenterol. 2019. PMID: 31275589 Free PMC article.
Epithelial cell transforming 2 is regulated by Yes-associated protein 1 and mediates pancreatic cancer progression and metastasis.
Li C, Peng Z, Wang Y, Lam G, Nissen N, Tang J, Yuan X, Lewis M, Greene MI, Pandol SJ, Wang Q. Li C, et al. Among authors: yuan x. Am J Physiol Gastrointest Liver Physiol. 2021 Mar 1;320(3):G380-G395. doi: 10.1152/ajpgi.00185.2020. Epub 2021 Jan 27. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33501895 Free PMC article.
Receptor-interacting protein kinase 2 (RIPK2) stabilizes c-Myc and is a therapeutic target in prostate cancer metastasis.
Yan Y, Zhou B, Qian C, Vasquez A, Kamra M, Chatterjee A, Lee YJ, Yuan X, Ellis L, Di Vizio D, Posadas EM, Kyprianou N, Knudsen BS, Shah K, Murali R, Gertych A, You S, Freeman MR, Yang W. Yan Y, et al. Among authors: yuan x. Nat Commun. 2022 Feb 3;13(1):669. doi: 10.1038/s41467-022-28340-6. Nat Commun. 2022. PMID: 35115556 Free PMC article.
Quantitative imaging for development of companion diagnostics to drugs targeting HGF/MET.
Huang F, Ma Z, Pollan S, Yuan X, Swartwood S, Gertych A, Rodriguez M, Mallick J, Bhele S, Guindi M, Dhall D, Walts AE, Bose S, de Peralta Venturina M, Marchevsky AM, Luthringer DJ, Feller SM, Berman B, Freeman MR, Alvord WG, Vande Woude G, Amin MB, Knudsen BS. Huang F, et al. Among authors: yuan x. J Pathol Clin Res. 2016 Jul 1;2(4):210-222. doi: 10.1002/cjp2.49. eCollection 2016 Oct. J Pathol Clin Res. 2016. PMID: 27785366 Free PMC article.
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