Yuan X - Search Results

1

Recent Advances of SHP2 Inhibitors in Cancer Therapy: Current Development and Clinical Application.

Yuan X, Bu H, Zhou J, Yang CY, Zhang H. Yuan X, et al. J Med Chem. 2020 Oct 22;63(20):11368-11396. doi: 10.1021/acs.jmedchem.0c00249. Epub 2020 Jun 10. J Med Chem. 2020. PMID: 32460492 Review.

2

Targeting the immunity protein kinases for immuno-oncology.

Yuan X, Wu H, Bu H, Zhou J, Zhang H. Yuan X, et al. Eur J Med Chem. 2019 Feb 1;163:413-427. doi: 10.1016/j.ejmech.2018.11.072. Epub 2018 Dec 4. Eur J Med Chem. 2019. PMID: 30530193 Review.

3

Design, synthesis and biological evaluation of pyridone-aminal derivatives as MNK1/2 inhibitors.

Yuan X, Wu H, Bu H, Zheng P, Zhou J, Zhang H. Yuan X, et al. Bioorg Med Chem. 2019 Apr 1;27(7):1211-1225. doi: 10.1016/j.bmc.2019.02.007. Epub 2019 Feb 2. Bioorg Med Chem. 2019. PMID: 30824167

4

Design, synthesis and biological evaluation of imidazo[1,5-a]pyrazin-8(7H)-one derivatives as BRD9 inhibitors.

Zheng P, Zhang J, Ma H, Yuan X, Chen P, Zhou J, Zhang H. Zheng P, et al. Among authors: yuan x. Bioorg Med Chem. 2019 Apr 1;27(7):1391-1404. doi: 10.1016/j.bmc.2019.02.045. Epub 2019 Feb 21. Bioorg Med Chem. 2019. PMID: 30824168

5

Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors.

Wei Q, Mei L, Chen P, Yuan X, Zhang H, Zhou J. Wei Q, et al. Among authors: yuan x. Bioorg Chem. 2020 Aug;101:103943. doi: 10.1016/j.bioorg.2020.103943. Epub 2020 May 15. Bioorg Chem. 2020. PMID: 32554277

6

Design, synthesis and biological evaluation of imidazopyridazine derivatives containing isoquinoline group as potent MNK1/2 inhibitors.

Bu H, Yuan X, Wu H, Zhou J, Zhang H. Bu H, et al. Among authors: yuan x. Bioorg Med Chem. 2021 Jun 15;40:116186. doi: 10.1016/j.bmc.2021.116186. Epub 2021 May 2. Bioorg Med Chem. 2021. PMID: 33971490

7

Corrigendum to "Design, synthesis and biological evaluation of imidazopyridazine derivatives containing isoquinoline group as potent MNK1/2 inhibitors" [Bioorg. Med. Chem. 40 (2021) 116186].

Bu H, Yuan X, Wu H, Zhou J, Zhang H. Bu H, et al. Among authors: yuan x. Bioorg Med Chem. 2022 Jan 15;54:116578. doi: 10.1016/j.bmc.2021.116578. Epub 2021 Dec 15. Bioorg Med Chem. 2022. PMID: 34920926 No abstract available.

8

Design, Synthesis, and Biological Evaluation of Apcin-Based CDC20 Inhibitors.

Bhuniya R, Yuan X, Bai L, Howie KL, Wang R, Li W, Park F, Yang CY. Bhuniya R, et al. Among authors: yuan x. ACS Med Chem Lett. 2022 Jan 18;13(2):188-195. doi: 10.1021/acsmedchemlett.1c00544. eCollection 2022 Feb 10. ACS Med Chem Lett. 2022. PMID: 35178174 Free PMC article.

9

Computational Cosolvent Mapping Analysis Leads to Identify Salicylic Acid Analogs as Weak Inhibitors of ST2 and IL33 Binding.

Yuan X, Chinnaswamy K, Stuckey JA, Yang CY. Yuan X, et al. J Phys Chem B. 2022 Mar 31;126(12):2394-2406. doi: 10.1021/acs.jpcb.2c00341. Epub 2022 Mar 16. J Phys Chem B. 2022. PMID: 35294837 Free PMC article.

10

Structure-Activity relationship of 1-(Furan-2ylmethyl)Pyrrolidine-Based Stimulation-2 (ST2) inhibitors for treating graft versus host disease.

Yuan X, Jiang H, Fu D, Robida A, Rajanayake K, Yuan H, Wen B, Sun D, Watch BT, Chinnaswamy K, Stuckey JA, Paczesny S, Rech JC, Yang CY. Yuan X, et al. Among authors: yuan h. Bioorg Med Chem. 2022 Oct 1;71:116942. doi: 10.1016/j.bmc.2022.116942. Epub 2022 Jul 22. Bioorg Med Chem. 2022. PMID: 35930851 Free PMC article.

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