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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis.
Zeisberg EM, Tarnavski O, Zeisberg M, Dorfman AL, McMullen JR, Gustafsson E, Chandraker A, Yuan X, Pu WT, Roberts AB, Neilson EG, Sayegh MH, Izumo S, Kalluri R. Zeisberg EM, et al. Among authors: yuan x. Nat Med. 2007 Aug;13(8):952-61. doi: 10.1038/nm1613. Epub 2007 Jul 29. Nat Med. 2007. PMID: 17660828
Homeostatic proliferation is a barrier to transplantation tolerance.
Wu Z, Bensinger SJ, Zhang J, Chen C, Yuan X, Huang X, Markmann JF, Kassaee A, Rosengard BR, Hancock WW, Sayegh MH, Turka LA. Wu Z, et al. Among authors: yuan x. Nat Med. 2004 Jan;10(1):87-92. doi: 10.1038/nm965. Epub 2003 Nov 30. Nat Med. 2004. PMID: 14647496 Free PMC article.
The novel costimulatory programmed death ligand 1/B7.1 pathway is functional in inhibiting alloimmune responses in vivo.
Yang J, Riella LV, Chock S, Liu T, Zhao X, Yuan X, Paterson AM, Watanabe T, Vanguri V, Yagita H, Azuma M, Blazar BR, Freeman GJ, Rodig SJ, Sharpe AH, Chandraker A, Sayegh MH. Yang J, et al. Among authors: yuan x. J Immunol. 2011 Aug 1;187(3):1113-9. doi: 10.4049/jimmunol.1100056. Epub 2011 Jun 22. J Immunol. 2011. PMID: 21697455 Free PMC article.
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