Yuan SH - Search Results

1

Safety, Tolerability, and Immunogenicity of the ACI-24 Vaccine in Adults With Down Syndrome: A Phase 1b Randomized Clinical Trial.

Rafii MS, Sol O, Mobley WC, Delpretti S, Skotko BG, Burke AD, Sabbagh MN, Yuan SH, Rissman RA, Pulsifer M, Evans C, Evans AC, Beth G, Fournier N, Gray JA, Dos Santos AM, Hliva V, Vukicevic M, Kosco-Vilbois M, Streffer J, Pfeifer A, Feldman HH. Rafii MS, et al. Among authors: yuan sh. JAMA Neurol. 2022 Jun 1;79(6):565-574. doi: 10.1001/jamaneurol.2022.0983. JAMA Neurol. 2022. PMID: 35532913 Free PMC article. Clinical Trial.

2

Extracellular Vesicles Isolated from Familial Alzheimer's Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain.

Aulston B, Liu Q, Mante M, Florio J, Rissman RA, Yuan SH. Aulston B, et al. Among authors: yuan sh. J Alzheimers Dis. 2019;72(2):575-585. doi: 10.3233/JAD-190656. J Alzheimers Dis. 2019. PMID: 31594233 Free PMC article.

3

Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses.

Podvin S, Jones A, Liu Q, Aulston B, Ransom L, Ames J, Shen G, Lietz CB, Jiang Z, O'Donoghue AJ, Winston C, Ikezu T, Rissman RA, Yuan S, Hook V. Podvin S, et al. Mol Cell Proteomics. 2020 Jun;19(6):1017-1034. doi: 10.1074/mcp.RA120.002079. Epub 2020 Apr 15. Mol Cell Proteomics. 2020. PMID: 32295833 Free PMC article.

4

[No title available]

[No authors listed] [No authors listed] PMID: 33451707

5

Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons.

Podvin S, Jones A, Liu Q, Aulston B, Mosier C, Ames J, Winston C, Lietz CB, Jiang Z, O'Donoghue AJ, Ikezu T, Rissman RA, Yuan SH, Hook V. Podvin S, et al. Among authors: yuan sh. ACS Omega. 2021 May 13;6(20):13033-13056. doi: 10.1021/acsomega.1c00660. eCollection 2021 May 25. ACS Omega. 2021. PMID: 34056454 Free PMC article.

6

Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers.

Liu Q, Waltz S, Woodruff G, Ouyang J, Israel MA, Herrera C, Sarsoza F, Tanzi RE, Koo EH, Ringman JM, Goldstein LS, Wagner SL, Yuan SH. Liu Q, et al. Among authors: yuan sh. JAMA Neurol. 2014 Dec;71(12):1481-9. doi: 10.1001/jamaneurol.2014.2482. JAMA Neurol. 2014. PMID: 25285942 Free PMC article.

7

Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo.

Winston CN, Aulston B, Rockenstein EM, Adame A, Prikhodko O, Dave KN, Mishra P, Rissman RA, Yuan SH. Winston CN, et al. Among authors: yuan sh. J Alzheimers Dis. 2019;67(2):541-553. doi: 10.3233/JAD-180776. J Alzheimers Dis. 2019. PMID: 30584143 Free PMC article.

8

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation.

Reilly P, Winston CN, Baron KR, Trejo M, Rockenstein EM, Akers JC, Kfoury N, Diamond M, Masliah E, Rissman RA, Yuan SH. Reilly P, et al. Among authors: yuan sh. Neurobiol Dis. 2017 Oct;106:222-234. doi: 10.1016/j.nbd.2017.06.005. Epub 2017 Jun 10. Neurobiol Dis. 2017. PMID: 28610892 Free PMC article.

9

A Case of Frontotemporal Lobar Degeneration With FUS-Positive Pathology (FTLD-FET) With Corticobasal Features and Language Deficits.

Goodwill V, Coughlin D, Pizzo D, Galasko D, Hansen LA, Yuan SH, Hiniker A. Goodwill V, et al. Among authors: yuan sh. J Neuropathol Exp Neurol. 2021 Sep 27;80(9):890-892. doi: 10.1093/jnen/nlab034. J Neuropathol Exp Neurol. 2021. PMID: 33969424 Free PMC article. No abstract available.

10

The presenilin-1 ΔE9 mutation results in reduced γ-secretase activity, but not total loss of PS1 function, in isogenic human stem cells.

Woodruff G, Young JE, Martinez FJ, Buen F, Gore A, Kinaga J, Li Z, Yuan SH, Zhang K, Goldstein LS. Woodruff G, et al. Among authors: yuan sh. Cell Rep. 2013 Nov 27;5(4):974-85. doi: 10.1016/j.celrep.2013.10.018. Epub 2013 Nov 14. Cell Rep. 2013. PMID: 24239350 Free PMC article.

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