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Broad-spectrum humanized monoclonal neutralizing antibody against SARS-CoV-2 variants, including the Omicron variant.
Wen K, Cai JP, Fan X, Zhang X, Luo C, Tang KM, Shuai H, Chen LL, Zhang RR, Situ J, Tsoi HW, Wang K, Chan JF, Yuan S, Yuen KY, Zhou H, To KK. Wen K, et al. Among authors: yuan s. Front Cell Infect Microbiol. 2023 Aug 14;13:1213806. doi: 10.3389/fcimb.2023.1213806. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37645378 Free PMC article.
Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo.
Yuan S, Chan JF, den-Haan H, Chik KK, Zhang AJ, Chan CC, Poon VK, Yip CC, Mak WW, Zhu Z, Zou Z, Tee KM, Cai JP, Chan KH, de la Peña J, Pérez-Sánchez H, Cerón-Carrasco JP, Yuen KY. Yuan S, et al. Antiviral Res. 2017 Sep;145:33-43. doi: 10.1016/j.antiviral.2017.07.007. Epub 2017 Jul 14. Antiviral Res. 2017. PMID: 28712942
Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells.
Chu H, Chan CM, Zhang X, Wang Y, Yuan S, Zhou J, Au-Yeung RK, Sze KH, Yang D, Shuai H, Hou Y, Li C, Zhao X, Poon VK, Leung SP, Yeung ML, Yan J, Lu G, Jin DY, Gao GF, Chan JF, Yuen KY. Chu H, et al. Among authors: yuan s. J Biol Chem. 2018 Jul 27;293(30):11709-11726. doi: 10.1074/jbc.RA118.001897. Epub 2018 Jun 10. J Biol Chem. 2018. PMID: 29887526 Free PMC article.
7,907 results