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Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets.
Wang T, Gross C, Desai AA, Zemskov E, Wu X, Garcia AN, Jacobson JR, Yuan JX, Garcia JG, Black SM. Wang T, et al. Among authors: yuan jx. Am J Physiol Lung Cell Mol Physiol. 2017 Apr 1;312(4):L452-L476. doi: 10.1152/ajplung.00231.2016. Epub 2016 Dec 15. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 27979857 Free PMC article. Review.
Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury.
Kumar S, Sun X, Noonepalle SK, Lu Q, Zemskov E, Wang T, Aggarwal S, Gross C, Sharma S, Desai AA, Hou Y, Dasarathy S, Qu N, Reddy V, Lee SG, Cherian-Shaw M, Yuan JX, Catravas JD, Rafikov R, Garcia JGN, Black SM. Kumar S, et al. Among authors: yuan jx. Free Radic Biol Med. 2017 Jan;102:217-228. doi: 10.1016/j.freeradbiomed.2016.11.008. Epub 2016 Nov 9. Free Radic Biol Med. 2017. PMID: 27838434 Free PMC article.
LPS-induced Acute Lung Injury Involves NF-κB-mediated Downregulation of SOX18.
Gross CM, Kellner M, Wang T, Lu Q, Sun X, Zemskov EA, Noonepalle S, Kangath A, Kumar S, Gonzalez-Garay M, Desai AA, Aggarwal S, Gorshkov B, Klinger C, Verin AD, Catravas JD, Jacobson JR, Yuan JX, Rafikov R, Garcia JGN, Black SM. Gross CM, et al. Among authors: yuan jx. Am J Respir Cell Mol Biol. 2018 May;58(5):614-624. doi: 10.1165/rcmb.2016-0390OC. Am J Respir Cell Mol Biol. 2018. PMID: 29115856 Free PMC article.
Asymmetric Dimethylarginine Stimulates Akt1 Phosphorylation via Heat Shock Protein 70-Facilitated Carboxyl-Terminal Modulator Protein Degradation in Pulmonary Arterial Endothelial Cells.
Sun X, Kellner M, Desai AA, Wang T, Lu Q, Kangath A, Qu N, Klinger C, Fratz S, Yuan JX, Jacobson JR, Garcia JG, Rafikov R, Fineman JR, Black SM. Sun X, et al. Among authors: yuan jx. Am J Respir Cell Mol Biol. 2016 Aug;55(2):275-87. doi: 10.1165/rcmb.2015-0185OC. Am J Respir Cell Mol Biol. 2016. PMID: 26959555 Free PMC article.
Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension.
Tang H, Yamamura A, Yamamura H, Song S, Fraidenburg DR, Chen J, Gu Y, Pohl NM, Zhou T, Jiménez-Pérez L, Ayon RJ, Desai AA, Goltzman D, Rischard F, Khalpey Z, Black SM, Garcia JG, Makino A, Yuan JX. Tang H, et al. Among authors: yuan jx. Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9):L846-59. doi: 10.1152/ajplung.00050.2016. Epub 2016 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 26968768 Free PMC article.
Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH.
Song S, Ayon RJ, Yamamura A, Yamamura H, Dash S, Babicheva A, Tang H, Sun X, Cordery AG, Khalpey Z, Black SM, Desai AA, Rischard F, McDermott KM, Garcia JG, Makino A, Yuan JX. Song S, et al. Among authors: yuan jx. Am J Physiol Lung Cell Mol Physiol. 2017 Mar 1;312(3):L309-L325. doi: 10.1152/ajplung.00357.2016. Epub 2016 Dec 15. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 27979859 Free PMC article.
Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition.
Tang H, Babicheva A, McDermott KM, Gu Y, Ayon RJ, Song S, Wang Z, Gupta A, Zhou T, Sun X, Dash S, Wang Z, Balistrieri A, Zheng Q, Cordery AG, Desai AA, Rischard F, Khalpey Z, Wang J, Black SM, Garcia JGN, Makino A, Yuan JX. Tang H, et al. Among authors: yuan jx. Am J Physiol Lung Cell Mol Physiol. 2018 Feb 1;314(2):L256-L275. doi: 10.1152/ajplung.00096.2017. Epub 2017 Oct 26. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29074488 Free PMC article.
Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension.
Wang Z, Yang K, Zheng Q, Zhang C, Tang H, Babicheva A, Jiang Q, Li M, Chen Y, Carr SG, Wu K, Zhang Q, Balistrieri A, Wang C, Song S, Ayon RJ, Desai AA, Black SM, Garcia JGN, Makino A, Yuan JX, Lu W, Wang J. Wang Z, et al. Among authors: yuan jx. Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L216-L228. doi: 10.1152/ajplung.00538.2017. Epub 2018 Oct 25. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 30358436 Free PMC article.
358 results