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Epithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis.
Liu Y, Peng J, Sun T, Li N, Zhang L, Ren J, Yuan H, Kan S, Pan Q, Li X, Ding Y, Jiang M, Cong X, Tan M, Ma Y, Fu D, Cai S, Xiao Y, Wang X, Qin J. Liu Y, et al. Among authors: yuan h. Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3796-E3805. doi: 10.1073/pnas.1700909114. Epub 2017 Apr 24. Proc Natl Acad Sci U S A. 2017. PMID: 28439030 Free PMC article.
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168.
Xie X, Hu H, Tong X, Li L, Liu X, Chen M, Yuan H, Xie X, Li Q, Zhang Y, Ouyang H, Wei M, Huang J, Liu P, Gan W, Liu Y, Xie A, Kuai X, Chirn GW, Zhou H, Zeng R, Hu R, Qin J, Meng FL, Wei W, Ji H, Gao D. Xie X, et al. Among authors: yuan h. Nat Cell Biol. 2018 Mar;20(3):320-331. doi: 10.1038/s41556-017-0033-8. Epub 2018 Feb 5. Nat Cell Biol. 2018. PMID: 29403037 Free PMC article.
Chromatin remodeling ATPase BRG1 and PTEN are synthetic lethal in prostate cancer.
Ding Y, Li N, Dong B, Guo W, Wei H, Chen Q, Yuan H, Han Y, Chang H, Kan S, Wang X, Pan Q, Wu P, Peng C, Qiu T, Li Q, Gao D, Xue W, Qin J. Ding Y, et al. Among authors: yuan h. J Clin Invest. 2019 Feb 1;129(2):759-773. doi: 10.1172/JCI123557. Epub 2019 Jan 14. J Clin Invest. 2019. PMID: 30496141 Free PMC article.
Identification of XAF1 as an endogenous AKT inhibitor.
Chen M, Wang K, Han Y, Yan S, Yuan H, Liu Q, Li L, Li N, Zhu H, Lu D, Wang K, Liu F, Luo D, Zhang Y, Jiang J, Li D, Zhang L, Ji H, Zhou H, Chen Y, Qin J, Gao D. Chen M, et al. Among authors: yuan h. Cell Rep. 2023 Jul 25;42(7):112690. doi: 10.1016/j.celrep.2023.112690. Epub 2023 Jun 27. Cell Rep. 2023. PMID: 37384528 Free article.
Targeting Microglial Metabolic Rewiring Synergizes with Immune-Checkpoint Blockade Therapy for Glioblastoma.
Ye Z, Ai X, Yang K, Yang Z, Fei F, Liao X, Qiu Z, Gimple RC, Yuan H, Huang H, Gong Y, Xiao C, Yue J, Huang L, Saulnier O, Wang W, Zhang P, Dai L, Wang X, Wang X, Ahn YH, You C, Xu J, Wan X, Taylor MD, Zhao L, Rich JN, Zhou S. Ye Z, et al. Among authors: yuan h. Cancer Discov. 2023 Apr 3;13(4):974-1001. doi: 10.1158/2159-8290.CD-22-0455. Cancer Discov. 2023. PMID: 36649564 Free PMC article.
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