Yu XM - Search Results

1

Transport and uptake of clausenamide enantiomers in CYP3A4-transfected Caco-2 cells: An insight into the efflux-metabolism alliance.

Hua F, Shi MJ, Zhu XL, Li M, Wang HX, Yu XM, Li Y, Zhu CJ. Hua F, et al. Among authors: yu xm. Biochem Pharmacol. 2015 Nov 1;98(1):224-30. doi: 10.1016/j.bcp.2015.08.102. Epub 2015 Aug 21. Biochem Pharmacol. 2015. PMID: 26301745

2

Stereoselective excretion and first-pass metabolism of clausenamide enantiomers.

Zhu CJ, Wang LJ, Hua F, Yu XM, Zhang JT. Zhu CJ, et al. Among authors: yu xm. Eur J Pharm Sci. 2013 Jul 16;49(4):761-6. doi: 10.1016/j.ejps.2013.04.033. Epub 2013 May 14. Eur J Pharm Sci. 2013. PMID: 23684935

3

Stereoselective Regulation of P-gp Activity by Clausenamide Enantiomers in Caco-2, KB/KBv and Brain Microvessel Endothelial Cells.

Zhu CJ, Hua F, Zhu XL, Li M, Wang HX, Yu XM, Li Y. Zhu CJ, et al. Among authors: yu xm. PLoS One. 2015 Aug 21;10(8):e0135866. doi: 10.1371/journal.pone.0135866. eCollection 2015. PLoS One. 2015. PMID: 26295572 Free PMC article.

4

The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect.

Chu S, Liu S, Duan W, Cheng Y, Jiang X, Zhu C, Tang K, Wang R, Xu L, Wang X, Yu X, Wu K, Wang Y, Wang M, Huang H, Zhang J. Chu S, et al. Pharmacol Ther. 2016 Jun;162:179-87. doi: 10.1016/j.pharmthera.2016.01.002. Epub 2016 Jan 23. Pharmacol Ther. 2016. PMID: 26812265 Review.

5

Inhibition of gastric tumor growth by a novel Hsp90 inhibitor.

Lu C, Liu D, Jin J, Deokar H, Zhang Y, Buolamwini JK, Yu X, Yan C, Chen X. Lu C, et al. Biochem Pharmacol. 2013 May 1;85(9):1246-56. doi: 10.1016/j.bcp.2013.02.003. Epub 2013 Feb 13. Biochem Pharmacol. 2013. PMID: 23415900 Free PMC article.

6

Total synthesis of herbimycin A.

Yan R, Bian C, Yu X. Yan R, et al. Org Lett. 2014 Jun 20;16(12):3280-3. doi: 10.1021/ol5012899. Epub 2014 Jun 9. Org Lett. 2014. PMID: 24911938

7

C15-methoxyphenylated 18-deoxy-herbimycin A analogues, their in vitro anticancer activity and heat shock protein 90 binding affinity.

Zhang Z, Xue N, Bian C, Yan R, Jin L, Chen X, Yu X. Zhang Z, et al. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4287-91. doi: 10.1016/j.bmcl.2016.07.040. Epub 2016 Jul 20. Bioorg Med Chem Lett. 2016. PMID: 27476419

8

Antiproliferative effect of HSP90 inhibitor Y306zh against pancreatic cancer is mediated by interruption of AKT and MAPK signaling pathways.

Xue N, Jin J, Liu D, Yan R, Zhang S, Yu X, Chen X. Xue N, et al. Curr Cancer Drug Targets. 2014;14(7):671-83. doi: 10.2174/1568009614666140908101523. Curr Cancer Drug Targets. 2014. PMID: 25219422

9

Chaperone-mediated autophagy degradation of IGF-1Rβ induced by NVP-AUY922 in pancreatic cancer.

Xue N, Lai F, Du T, Ji M, Liu D, Yan C, Zhang S, Yu X, Jin J, Chen X. Xue N, et al. Cell Mol Life Sci. 2019 Sep;76(17):3433-3447. doi: 10.1007/s00018-019-03080-x. Epub 2019 Apr 12. Cell Mol Life Sci. 2019. PMID: 30980109

10

Total Synthesis of Geldanamycin.

Zhang Z, Li Y, Zhang R, Yu X. Zhang Z, et al. J Org Chem. 2021 Nov 5;86(21):15063-15075. doi: 10.1021/acs.joc.1c01582. Epub 2021 Oct 16. J Org Chem. 2021. PMID: 34657428

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