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METTL3 (Methyltransferase Like 3)-Dependent N6-Methyladenosine Modification on Braf mRNA Promotes Macrophage Inflammatory Response and Atherosclerosis in Mice.
Li Q, Yu L, Gao A, Ren R, Zhang J, Cao L, Wang X, Liu Y, Qi W, Cai L, Li W, Wang W, Guo X, Su G, Yu X, Zhang J, Xi B, Zhang Y, Zhang M, Zhang C. Li Q, et al. Among authors: yu l, yu x. Arterioscler Thromb Vasc Biol. 2023 May;43(5):755-773. doi: 10.1161/ATVBAHA.122.318451. Epub 2023 Mar 23. Arterioscler Thromb Vasc Biol. 2023. PMID: 36951060
The role of aldehyde dehydrogenase 2 in cardiovascular disease.
Zhang J, Guo Y, Zhao X, Pang J, Pan C, Wang J, Wei S, Yu X, Zhang C, Chen Y, Yin H, Xu F. Zhang J, et al. Among authors: yu x. Nat Rev Cardiol. 2023 Jul;20(7):495-509. doi: 10.1038/s41569-023-00839-5. Epub 2023 Feb 13. Nat Rev Cardiol. 2023. PMID: 36781974 Review.
Unsaturated bond recognition leads to biased signal in a fatty acid receptor.
Mao C, Xiao P, Tao XN, Qin J, He QT, Zhang C, Guo SC, Du YQ, Chen LN, Shen DD, Yang ZS, Zhang HQ, Huang SM, He YH, Cheng J, Zhong YN, Shang P, Chen J, Zhang DL, Wang QL, Liu MX, Li GY, Guo Y, Xu HE, Wang C, Zhang C, Feng S, Yu X, Zhang Y, Sun JP. Mao C, et al. Among authors: yu x. Science. 2023 Apr 7;380(6640):eadd6220. doi: 10.1126/science.add6220. Epub 2023 Apr 7. Science. 2023. PMID: 36862765
Structural basis of amine odorant perception by a mammal olfactory receptor.
Guo L, Cheng J, Lian S, Liu Q, Lu Y, Zheng Y, Zhu K, Zhang M, Kong Y, Zhang C, Rong N, Zhuang Y, Fang G, Jiang J, Zhang T, Han X, Liu Z, Xia M, Liu S, Zhang L, Liberles SD, Yu X, Xu Y, Yang F, Li Q, Sun JP. Guo L, et al. Among authors: yu x. Nature. 2023 Jun;618(7963):193-200. doi: 10.1038/s41586-023-06106-4. Epub 2023 May 24. Nature. 2023. PMID: 37225986
Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.
Guo L, Zhang Y, Fang G, Tie L, Zhuang Y, Xue C, Liu Q, Zhang M, Zhu K, You C, Xu P, Yuan Q, Zhang C, Liu L, Rong N, Peng S, Liu Y, Wang C, Luo X, Lv Z, Kang D, Yu X, Zhang C, Jiang Y, Dong X, Zhou J, Liu Z, Yang F, Eric Xu H, Sun JP. Guo L, et al. Among authors: yu x. Nat Commun. 2023 Aug 17;14(1):5004. doi: 10.1038/s41467-023-40705-z. Nat Commun. 2023. PMID: 37591889 Free PMC article.
Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
Wang JL, Dou XD, Cheng J, Gao MX, Xu GF, Ding W, Ding JH, Li Y, Wang SH, Ji ZW, Zhao XY, Huo TY, Zhang CF, Liu YM, Sha XY, Gao JR, Zhang WH, Hao Y, Zhang C, Sun JP, Jiao N, Yu X. Wang JL, et al. Among authors: yu x. Nat Metab. 2023 Oct;5(10):1726-1746. doi: 10.1038/s42255-023-00899-4. Epub 2023 Sep 28. Nat Metab. 2023. PMID: 37770763
Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Yang Z, Wang JY, Yang F, Zhu KK, Wang GP, Guan Y, Ning SL, Lu Y, Li Y, Zhang C, Zheng Y, Zhou SH, Wang XW, Wang MW, Xiao P, Yi F, Zhang C, Zhang PJ, Xu F, Liu BH, Zhang H, Yu X, Gao N, Sun JP. Yang Z, et al. Among authors: yu x. Nat Chem Biol. 2024 Apr;20(4):484-492. doi: 10.1038/s41589-023-01456-6. Epub 2023 Nov 9. Nat Chem Biol. 2024. PMID: 37945893
Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Shang P, Rong N, Jiang JJ, Cheng J, Zhang MH, Kang D, Qi L, Guo L, Yang GM, Liu Q, Zhou Z, Li XB, Zhu KK, Meng QB, Han X, Yan W, Kong Y, Yang L, Wang X, Lei D, Feng X, Liu X, Yu X, Wang Y, Li Q, Shao ZH, Yang F, Sun JP. Shang P, et al. Among authors: yu x. Cell. 2023 Nov 22;186(24):5347-5362.e24. doi: 10.1016/j.cell.2023.10.014. Epub 2023 Nov 13. Cell. 2023. PMID: 37963465
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