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A double-blind, randomized, placebo and positive-controlled study in healthy volunteers to evaluate pharmacokinetic and pharmacodynamic properties of multiple oral doses of cetagliptin.
Lu J, Wang L, Zhou S, Zhou C, Xie L, Chen J, Tang D, Tian X, Xie D, Ding J, Wang T, Yu Q, Ding J, Shao F. Lu J, et al. Among authors: yu q. Br J Clin Pharmacol. 2022 Jun;88(6):2946-2958. doi: 10.1111/bcp.15209. Epub 2022 Feb 4. Br J Clin Pharmacol. 2022. PMID: 34965609 Free article. Clinical Trial.
First-in-Human, Single-Ascending Dose and Food Effect Studies to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Cetagliptin, a Dipeptidyl Peptidase-4 Inhibitor for the Treatment of Type 2 Diabetes Mellitus.
Wang L, Lu J, Zhou S, Zhao Y, Xie L, Zhou C, Chen J, Ding S, Xie D, Ding J, Yu Q, Shen H, Hao G, Shao F. Wang L, et al. Among authors: yu q. Clin Drug Investig. 2021 Nov;41(11):999-1010. doi: 10.1007/s40261-021-01088-5. Epub 2021 Oct 16. Clin Drug Investig. 2021. PMID: 34655432 Clinical Trial.
A randomized, double-blind, placebo controlled, phase 3 trial to evaluate the efficacy and safety of cetagliptin added to ongoing metformin therapy in patients with uncontrolled type 2 diabetes with metformin monotherapy.
Ji L, Lu J, Gao L, Yan X, Li J, Cheng Z, Zhang L, Tian J, Li P, Bai J, Xie D, Zhao J, Ding J, Yu Q, Wang T. Ji L, et al. Among authors: yu q. Diabetes Obes Metab. 2023 Dec;25(12):3788-3797. doi: 10.1111/dom.15274. Epub 2023 Sep 19. Diabetes Obes Metab. 2023. PMID: 37724698 Clinical Trial.
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