Yu M - Search Results

1

MAP kinase-interacting kinases--emerging targets against cancer.

Diab S, Kumarasiri M, Yu M, Teo T, Proud C, Milne R, Wang S. Diab S, et al. Among authors: yu m. Chem Biol. 2014 Apr 24;21(4):441-452. doi: 10.1016/j.chembiol.2014.01.011. Epub 2014 Mar 6. Chem Biol. 2014. PMID: 24613018 Review.

2

Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: synthesis, structure-activity relationships, and biological activities.

Lu T, Goh AW, Yu M, Adams J, Lam F, Teo T, Li P, Noll B, Zhong L, Diab S, Chahrour O, Hu A, Abbas AY, Liu X, Huang S, Sumby CJ, Milne R, Midgley C, Wang S. Lu T, et al. Among authors: yu m. J Med Chem. 2014 Mar 27;57(6):2275-91. doi: 10.1021/jm4019614. Epub 2014 Mar 10. J Med Chem. 2014. PMID: 24471873

3

Discovery of 5-(2-(phenylamino)pyrimidin-4-yl)thiazol-2(3H)-one derivatives as potent Mnk2 inhibitors: synthesis, SAR analysis and biological evaluation.

Diab S, Teo T, Kumarasiri M, Li P, Yu M, Lam F, Basnet SK, Sykes MJ, Albrecht H, Milne R, Wang S. Diab S, et al. Among authors: yu m. ChemMedChem. 2014 May;9(5):962-72. doi: 10.1002/cmdc.201300552. Epub 2014 Feb 12. ChemMedChem. 2014. PMID: 24677692

4

Pharmacologic co-inhibition of Mnks and mTORC1 synergistically suppresses proliferation and perturbs cell cycle progression in blast crisis-chronic myeloid leukemia cells.

Teo T, Yu M, Yang Y, Gillam T, Lam F, Sykes MJ, Wang S. Teo T, et al. Among authors: yu m. Cancer Lett. 2015 Feb 28;357(2):612-23. doi: 10.1016/j.canlet.2014.12.029. Epub 2014 Dec 16. Cancer Lett. 2015. PMID: 25527453

5

Targeting Pim kinases for cancer treatment: opportunities and challenges.

Le BT, Kumarasiri M, Adams JR, Yu M, Milne R, Sykes MJ, Wang S. Le BT, et al. Among authors: yu m. Future Med Chem. 2015;7(1):35-53. doi: 10.4155/fmc.14.145. Future Med Chem. 2015. PMID: 25582332 Review.

6

Discovery of 4-(dihydropyridinon-3-yl)amino-5-methylthieno[2,3-d]pyrimidine derivatives as potent Mnk inhibitors: synthesis, structure-activity relationship analysis and biological evaluation.

Yu M, Li P, Basnet SK, Kumarasiri M, Diab S, Teo T, Albrecht H, Wang S. Yu M, et al. Eur J Med Chem. 2015 May 5;95:116-26. doi: 10.1016/j.ejmech.2015.03.032. Epub 2015 Mar 17. Eur J Med Chem. 2015. PMID: 25800647

7

Pharmacologic Inhibition of MNKs in Acute Myeloid Leukemia.

Teo T, Lam F, Yu M, Yang Y, Basnet SK, Albrecht H, Sykes MJ, Wang S. Teo T, et al. Among authors: yu m. Mol Pharmacol. 2015 Aug;88(2):380-9. doi: 10.1124/mol.115.098012. Epub 2015 Jun 4. Mol Pharmacol. 2015. PMID: 26044548

8

Identification of a Highly Conserved Allosteric Binding Site on Mnk1 and Mnk2.

Basnet SK, Diab S, Schmid R, Yu M, Yang Y, Gillam TA, Teo T, Li P, Peat T, Albrecht H, Wang S. Basnet SK, et al. Among authors: yu m. Mol Pharmacol. 2015 Nov;88(5):935-48. doi: 10.1124/mol.115.100131. Epub 2015 Aug 12. Mol Pharmacol. 2015. PMID: 26268528

9

Targeting CDK6 in cancer: State of the art and new insights.

Tadesse S, Yu M, Kumarasiri M, Le BT, Wang S. Tadesse S, et al. Among authors: yu m. Cell Cycle. 2015;14(20):3220-30. doi: 10.1080/15384101.2015.1084445. Cell Cycle. 2015. PMID: 26315616 Free PMC article. Review.

10

An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis.

Teo T, Yang Y, Yu M, Basnet SK, Gillam T, Hou J, Schmid RM, Kumarasiri M, Diab S, Albrecht H, Sykes MJ, Wang S. Teo T, et al. Among authors: yu m. Eur J Med Chem. 2015 Oct 20;103:539-50. doi: 10.1016/j.ejmech.2015.09.008. Epub 2015 Sep 9. Eur J Med Chem. 2015. PMID: 26408454

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