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Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats.
Wong VKW, Qiu C, Xu SW, Law BYK, Zeng W, Wang H, Michelangeli F, Dias IRSR, Qu YQ, Chan TW, Han Y, Zhang N, Mok SWF, Chen X, Yu L, Pan H, Hamdoun S, Efferth T, Yu WJ, Zhang W, Li Z, Xie Y, Luo R, Jiang Q, Liu L. Wong VKW, et al. Among authors: yu l, yu wj. Br J Pharmacol. 2019 Aug;176(16):2922-2944. doi: 10.1111/bph.14718. Epub 2019 Jul 4. Br J Pharmacol. 2019. PMID: 31124139 Free PMC article.
Sirtuin 5 deficiency increases disease severity in rats with adjuvant-induced arthritis.
Zhang N, Zhang H, Law BYK, Dias IRSR, Qiu CL, Zeng W, Dan Pan H, Chen JY, Bai YF, Lv J, Qu LQ, Chen X, Huang Q, Zhang W, Yang LJ, Yu L, Han Y, Huang GX, Wang HM, Sun XL, Zhang Y, He HQ, Dan Luo W, Xiao Y, Zhou J, Xu T, Huang QC, Wu M, Huang ZS, Liu W, Wong VKW, Liu L. Zhang N, et al. Among authors: yu l. Cell Mol Immunol. 2020 Nov;17(11):1190-1192. doi: 10.1038/s41423-020-0380-4. Epub 2020 Feb 25. Cell Mol Immunol. 2020. PMID: 32099074 Free PMC article. No abstract available.
Lychee seed polyphenol protects the blood-brain barrier through inhibiting Aβ(25-35)-induced NLRP3 inflammasome activation via the AMPK/mTOR/ULK1-mediated autophagy in bEnd.3 cells and APP/PS1 mice.
Xiong R, Zhou XG, Tang Y, Wu JM, Sun YS, Teng JF, Pan R, Law BY, Zhao Y, Qiu WQ, Wang XL, Liu S, Wang YL, Yu L, Yu CL, Mei QB, Qin DL, Wu AG. Xiong R, et al. Among authors: yu l, yu cl. Phytother Res. 2021 Feb;35(2):954-973. doi: 10.1002/ptr.6849. Epub 2020 Sep 6. Phytother Res. 2021. PMID: 32893437
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