Yu J - Search Results

1

Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.

Fan S, Yan Y, Xia Y, Zhou Z, Luo L, Zhu M, Han Y, Yao D, Zhang L, Fang M, Peng L, Yu J, Liu Y, Gao X, Guan H, Li H, Wang C, Wu X, Zhu H, Cao Y, Huang C. Fan S, et al. Among authors: yu j. Nat Commun. 2023 Jun 8;14(1):3368. doi: 10.1038/s41467-023-39118-9. Nat Commun. 2023. PMID: 37291126 Free PMC article.

2

Second messenger Ap₄A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells.

Yu J, Liu Z, Liang Y, Luo F, Zhang J, Tian C, Motzik A, Zheng M, Kang J, Zhong G, Liu C, Fang P, Guo M, Razin E, Wang J. Yu J, et al. Nat Commun. 2019 Oct 11;10(1):4664. doi: 10.1038/s41467-019-12710-8. Nat Commun. 2019. PMID: 31604935 Free PMC article.

3

A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules.

Liang M, Li Z, Wang W, Liu J, Liu L, Zhu G, Karthik L, Wang M, Wang KF, Wang Z, Yu J, Shuai Y, Yu J, Zhang L, Yang Z, Li C, Zhang Q, Shi T, Zhou L, Xie F, Dai H, Liu X, Zhang J, Liu G, Zhuo Y, Zhang B, Liu C, Li S, Xia X, Tong Y, Liu Y, Alterovitz G, Tan GY, Zhang LX. Liang M, et al. Among authors: yu j. Nat Commun. 2019 Aug 14;10(1):3672. doi: 10.1038/s41467-019-11648-1. Nat Commun. 2019. PMID: 31413315 Free PMC article.

4

Structure of M^pro from SARS-CoV-2 and discovery of its inhibitors.

Jin Z, Du X, Xu Y, Deng Y, Liu M, Zhao Y, Zhang B, Li X, Zhang L, Peng C, Duan Y, Yu J, Wang L, Yang K, Liu F, Jiang R, Yang X, You T, Liu X, Yang X, Bai F, Liu H, Liu X, Guddat LW, Xu W, Xiao G, Qin C, Shi Z, Jiang H, Rao Z, Yang H. Jin Z, et al. Among authors: yu j. Nature. 2020 Jun;582(7811):289-293. doi: 10.1038/s41586-020-2223-y. Epub 2020 Apr 9. Nature. 2020. PMID: 32272481

5

Unique structure of active platinum-bismuth site for oxidation of carbon monoxide.

Nan B, Fu Q, Yu J, Shu M, Zhou LL, Li J, Wang WW, Jia CJ, Ma C, Chen JX, Li L, Si R. Nan B, et al. Among authors: yu j. Nat Commun. 2021 Jun 7;12(1):3342. doi: 10.1038/s41467-021-23696-7. Nat Commun. 2021. PMID: 34099668 Free PMC article.

6

Transformation of a Dopamine D₂ Receptor Agonist to Partial Agonists as Novel Antipsychotic Agents.

Liu R, Qi J, Wang H, Fan L, Zhang P, Yu J, Tan L, Wang S, Cheng J. Liu R, et al. Among authors: yu j. J Med Chem. 2023 May 11;66(9):6274-6287. doi: 10.1021/acs.jmedchem.3c00098. Epub 2023 May 2. J Med Chem. 2023. PMID: 37130037

7

Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur.

Jin Z, Zhao Y, Sun Y, Zhang B, Wang H, Wu Y, Zhu Y, Zhu C, Hu T, Du X, Duan Y, Yu J, Yang X, Yang X, Yang K, Liu X, Guddat LW, Xiao G, Zhang L, Yang H, Rao Z. Jin Z, et al. Among authors: yu j. Nat Struct Mol Biol. 2020 Jun;27(6):529-532. doi: 10.1038/s41594-020-0440-6. Epub 2020 May 7. Nat Struct Mol Biol. 2020. PMID: 32382072

8

Determination of the melanocortin-4 receptor structure identifies Ca²⁺ as a cofactor for ligand binding.

Yu J, Gimenez LE, Hernandez CC, Wu Y, Wein AH, Han GW, McClary K, Mittal SR, Burdsall K, Stauch B, Wu L, Stevens SN, Peisley A, Williams SY, Chen V, Millhauser GL, Zhao S, Cone RD, Stevens RC. Yu J, et al. Science. 2020 Apr 24;368(6489):428-433. doi: 10.1126/science.aaz8995. Science. 2020. PMID: 32327598 Free PMC article.

9

[Synthesis of "danshensu" derivatives].

Yu JM, Xue F, Dai HJ. Yu JM, et al. Yao Xue Xue Bao. 1991;26(7):552-6. Yao Xue Xue Bao. 1991. PMID: 1805515 Chinese.

10

Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists.

Claff T, Yu J, Blais V, Patel N, Martin C, Wu L, Han GW, Holleran BJ, Van der Poorten O, White KL, Hanson MA, Sarret P, Gendron L, Cherezov V, Katritch V, Ballet S, Liu ZJ, Müller CE, Stevens RC. Claff T, et al. Among authors: yu j. Sci Adv. 2019 Nov 27;5(11):eaax9115. doi: 10.1126/sciadv.aax9115. eCollection 2019 Nov. Sci Adv. 2019. PMID: 31807708 Free PMC article.

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