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Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies.
Abdellatif KR, Chowdhury MA, Dong Y, Das D, Yu G, Velázquez C, Suresh MR, Knaus EE. Abdellatif KR, et al. Among authors: yu g. Bioorg Med Chem. 2009 Jul 15;17(14):5182-8. doi: 10.1016/j.bmc.2009.05.046. Epub 2009 May 27. Bioorg Med Chem. 2009. PMID: 19500994
Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
Chowdhury MA, Abdellatif KR, Dong Y, Das D, Yu G, Velázquez CA, Suresh MR, Knaus EE. Chowdhury MA, et al. Among authors: yu g. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6855-61. doi: 10.1016/j.bmcl.2009.10.083. Epub 2009 Oct 23. Bioorg Med Chem Lett. 2009. PMID: 19884005
9,518 results