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Lirentelimab for severe and chronic forms of allergic conjunctivitis.
Anesi SD, Tauber J, Nguyen QD, Chang P, Berdy GJ, Lin CC, Chu DS, Levine HT, Fernandez AD, Roy N, Asbell PA, Kantor AM, Chang AT, Singh B, Youngblood BA, Jeng BH, Jhanji V, Rasmussen HS, Foster CS. Anesi SD, et al. Among authors: youngblood ba. J Allergy Clin Immunol. 2022 Sep;150(3):631-639. doi: 10.1016/j.jaci.2022.03.021. Epub 2022 Apr 4. J Allergy Clin Immunol. 2022. PMID: 35390403 Free article. Clinical Trial.
Eosinophil and mast cell Siglecs: From biology to drug target.
O'Sullivan JA, Chang AT, Youngblood BA, Bochner BS. O'Sullivan JA, et al. Among authors: youngblood ba. J Leukoc Biol. 2020 Jul;108(1):73-81. doi: 10.1002/JLB.2MR0120-352RR. Epub 2020 Jan 22. J Leukoc Biol. 2020. PMID: 31965606 Free PMC article. Review.
Discovery, Function, and Therapeutic Targeting of Siglec-8.
Youngblood BA, Leung J, Falahati R, Williams J, Schanin J, Brock EC, Singh B, Chang AT, O'Sullivan JA, Schleimer RP, Tomasevic N, Bebbington CR, Bochner BS. Youngblood BA, et al. Cells. 2020 Dec 24;10(1):19. doi: 10.3390/cells10010019. Cells. 2020. PMID: 33374255 Free PMC article. Review.
Siglecs in allergy and asthma.
Bochner BS, O'Sullivan JA, Chang AT, Youngblood BA. Bochner BS, et al. Among authors: youngblood ba. Mol Aspects Med. 2023 Apr;90:101104. doi: 10.1016/j.mam.2022.101104. Epub 2022 Jul 11. Mol Aspects Med. 2023. PMID: 35835621 Free PMC article. Review.
Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies.
Legrand F, Cao Y, Wechsler JB, Zhu X, Zimmermann N, Rampertaap S, Monsale J, Romito K, Youngblood BA, Brock EC, Makiya MA, Tomasevic N, Bebbington C, Maric I, Metcalfe DD, Bochner BS, Klion AD. Legrand F, et al. Among authors: youngblood ba. J Allergy Clin Immunol. 2019 Jun;143(6):2227-2237.e10. doi: 10.1016/j.jaci.2018.10.066. Epub 2018 Dec 10. J Allergy Clin Immunol. 2019. PMID: 30543818 Free PMC article.
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
Youngblood BA, Brock EC, Leung J, Falahati R, Bryce PJ, Bright J, Williams J, Shultz LD, Greiner DL, Brehm MA, Bebbington C, Tomasevic N. Youngblood BA, et al. Int Arch Allergy Immunol. 2019;180(2):91-102. doi: 10.1159/000501637. Epub 2019 Aug 9. Int Arch Allergy Immunol. 2019. PMID: 31401630 Free PMC article.
Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody.
Gebremeskel S, Schanin J, Coyle KM, Butuci M, Luu T, Brock EC, Xu A, Wong A, Leung J, Korver W, Morin RD, Schleimer RP, Bochner BS, Youngblood BA. Gebremeskel S, et al. Among authors: youngblood ba. Front Immunol. 2021 Mar 10;12:650331. doi: 10.3389/fimmu.2021.650331. eCollection 2021. Front Immunol. 2021. PMID: 33777047 Free PMC article.
41 results