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Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.
Zhang T, Kwiatkowski N, Olson CM, Dixon-Clarke SE, Abraham BJ, Greifenberg AK, Ficarro SB, Elkins JM, Liang Y, Hannett NM, Manz T, Hao M, Bartkowiak B, Greenleaf AL, Marto JA, Geyer M, Bullock AN, Young RA, Gray NS. Zhang T, et al. Among authors: young ra. Nat Chem Biol. 2016 Oct;12(10):876-84. doi: 10.1038/nchembio.2166. Epub 2016 Aug 29. Nat Chem Biol. 2016. PMID: 27571479 Free PMC article.
A kinase-cyclin pair in the RNA polymerase II holoenzyme.
Liao SM, Zhang J, Jeffery DA, Koleske AJ, Thompson CM, Chao DM, Viljoen M, van Vuuren HJ, Young RA. Liao SM, et al. Among authors: young ra. Nature. 1995 Mar 9;374(6518):193-6. doi: 10.1038/374193a0. Nature. 1995. PMID: 7877695
Serial regulation of transcriptional regulators in the yeast cell cycle.
Simon I, Barnett J, Hannett N, Harbison CT, Rinaldi NJ, Volkert TL, Wyrick JJ, Zeitlinger J, Gifford DK, Jaakkola TS, Young RA. Simon I, et al. Among authors: young ra. Cell. 2001 Sep 21;106(6):697-708. doi: 10.1016/s0092-8674(01)00494-9. Cell. 2001. PMID: 11572776 Free article.
Transcriptional regulatory networks in Saccharomyces cerevisiae.
Lee TI, Rinaldi NJ, Robert F, Odom DT, Bar-Joseph Z, Gerber GK, Hannett NM, Harbison CT, Thompson CM, Simon I, Zeitlinger J, Jennings EG, Murray HL, Gordon DB, Ren B, Wyrick JJ, Tagne JB, Volkert TL, Fraenkel E, Gifford DK, Young RA. Lee TI, et al. Among authors: young ra. Science. 2002 Oct 25;298(5594):799-804. doi: 10.1126/science.1075090. Science. 2002. PMID: 12399584
Transcriptional regulatory code of a eukaryotic genome.
Harbison CT, Gordon DB, Lee TI, Rinaldi NJ, Macisaac KD, Danford TW, Hannett NM, Tagne JB, Reynolds DB, Yoo J, Jennings EG, Zeitlinger J, Pokholok DK, Kellis M, Rolfe PA, Takusagawa KT, Lander ES, Gifford DK, Fraenkel E, Young RA. Harbison CT, et al. Among authors: young ra. Nature. 2004 Sep 2;431(7004):99-104. doi: 10.1038/nature02800. Nature. 2004. PMID: 15343339 Free PMC article.
Global position and recruitment of HATs and HDACs in the yeast genome.
Robert F, Pokholok DK, Hannett NM, Rinaldi NJ, Chandy M, Rolfe A, Workman JL, Gifford DK, Young RA. Robert F, et al. Among authors: young ra. Mol Cell. 2004 Oct 22;16(2):199-209. doi: 10.1016/j.molcel.2004.09.021. Mol Cell. 2004. PMID: 15494307 Free PMC article.
697 results