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Loss of G0/G1 switch gene 2 (G0S2) promotes disease progression and drug resistance in chronic myeloid leukaemia (CML) by disrupting glycerophospholipid metabolism.
Gonzalez MA, Olivas IM, Bencomo-Alvarez AE, Rubio AJ, Barreto-Vargas C, Lopez JL, Dang SK, Solecki JP, McCall E, Astudillo G, Velazquez VV, Schenkel K, Reffell K, Perkins M, Nguyen N, Apaflo JN, Alvidrez E, Young JE, Lara JJ, Yan D, Senina A, Ahmann J, Varley KE, Mason CC, Eide CA, Druker BJ, Nurunnabi M, Padilla O, Bajpeyi S, Eiring AM. Gonzalez MA, et al. Among authors: young je. Clin Transl Med. 2022 Dec;12(12):e1146. doi: 10.1002/ctm2.1146. Clin Transl Med. 2022. PMID: 36536477 Free PMC article.
19S Proteasome Subunits as Oncogenes and Prognostic Biomarkers in FLT3-Mutated Acute Myeloid Leukemia (AML).
Lara JJ, Bencomo-Alvarez AE, Gonzalez MA, Olivas IM, Young JE, Lopez JL, Velazquez VV, Glovier S, Keivan M, Rubio AJ, Dang SK, Solecki JP, Allen JC, Tapia DN, Tychhon B, Astudillo GE, Jordan C, Chandrashekar DS, Eiring AM. Lara JJ, et al. Among authors: young je. Int J Mol Sci. 2022 Nov 23;23(23):14586. doi: 10.3390/ijms232314586. Int J Mol Sci. 2022. PMID: 36498916 Free PMC article.
Far-red and sensitive sensor for monitoring real time H2O2 dynamics with subcellular resolution and in multi-parametric imaging applications.
Lee JD, Nguyen A, Jin ZR, Moghadasi A, Gibbs CE, Wait SJ, Evitts KM, Asencio A, Bremner SB, Zuniga S, Chavan V, Williams A, Smith N, Regnier M, Young JE, Mack D, Nance E, Boyle PM, Berndt A. Lee JD, et al. Among authors: young je. bioRxiv [Preprint]. 2024 Feb 8:2024.02.06.579232. doi: 10.1101/2024.02.06.579232. bioRxiv. 2024. PMID: 38370715 Free PMC article. Preprint.
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
Bashore FM, Katis VL, Du Y, Sikdar A, Wang D, Bradshaw WJ, Rygiel KA, Leisner TM, Chalk R, Mishra S, Williams CA, Gileadi O, Brennan PE, Wiley JC, Gockley J, Cary GA, Carter GW, Young JE, Pearce KH, Fu H; Emory-Sage-SGC TREAT-AD Center; Axtman AD. Bashore FM, et al. Among authors: young je. PLoS One. 2024 Feb 15;19(2):e0293548. doi: 10.1371/journal.pone.0293548. eCollection 2024. PLoS One. 2024. PMID: 38359047 Free PMC article.
Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring.
Lee JD, Won W, Kimball K, Wang Y, Yeboah F, Evitts KM, Neiswanger C, Schattauer S, Rappleye M, Bremner SB, Chun C, Smith N, Mack DL, Young JE, Lee CJ, Chavkin C, Berndt A. Lee JD, et al. Among authors: young je. bioRxiv [Preprint]. 2024 Feb 4:2024.01.31.578117. doi: 10.1101/2024.01.31.578117. bioRxiv. 2024. PMID: 38352381 Free PMC article. Preprint.
Single Cell RNA Sequencing Reveals Human Tooth Type Identity and Guides In Vitro hiPSC Derived Odontoblast Differentiation (iOB).
Hanson-Drury S, Patni AP, Lee DL, Alghadeer A, Zhao YT, Ehnes DD, Vo VN, Kim SY, Jithendra D, Phal A, Edman NI, Schlichthaerle T, Baker D, Young JE, Mathieu J, Ruohola-Baker H. Hanson-Drury S, et al. Among authors: young je. Front Dent Med. 2023;4:10.3389/fdmed.2023.1209503. doi: 10.3389/fdmed.2023.1209503. Epub 2023 Jul 20. Front Dent Med. 2023. PMID: 38259324 Free PMC article.
231 results