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Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.
Deja S, Fletcher JA, Kim CW, Kucejova B, Fu X, Mizerska M, Villegas M, Pudelko-Malik N, Browder N, Inigo-Vollmer M, Menezes CJ, Mishra P, Berglund ED, Browning JD, Thyfault JP, Young JD, Horton JD, Burgess SC. Deja S, et al. Among authors: young jd. Cell Metab. 2024 Mar 1:S1550-4131(24)00050-0. doi: 10.1016/j.cmet.2024.02.004. Online ahead of print. Cell Metab. 2024. PMID: 38447582 Free article.
Biochemical and metabolic characterization of a G6PC2 inhibitor.
Hawes EM, Rahim M, Haratipour Z, Orun AR, O'Rourke ML, Oeser JK, Kim K, Claxton DP, Blind RD, Young JD, O'Brien RM. Hawes EM, et al. Among authors: young jd. Biochimie. 2024 Mar 1;222:109-122. doi: 10.1016/j.biochi.2024.02.012. Online ahead of print. Biochimie. 2024. PMID: 38431189 Free article.
Senescence: No country for old cells.
Martel J, Ojcius DM, Young JD. Martel J, et al. Among authors: young jd. Biomed J. 2023 Dec 29;47(2):100697. doi: 10.1016/j.bj.2023.100697. Online ahead of print. Biomed J. 2023. PMID: 38160717 Free PMC article. No abstract available.
Lifestyle interventions to delay senescence.
Martel J, Ojcius DM, Young JD. Martel J, et al. Among authors: young jd. Biomed J. 2023 Nov 3;47(2):100676. doi: 10.1016/j.bj.2023.100676. Online ahead of print. Biomed J. 2023. PMID: 37925155 Free PMC article.
1,053 results