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Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies.
Temple WC, Nix MA, Naik A, Izgutdina A, Huang BJ, Wicaksono G, Phojanakong P, Serrano JAC, Young EP, Ramos E, Salangsang F, Steri V, Xirenayi S, Hermiston M, Logan AC, Stieglitz E, Wiita AP. Temple WC, et al. Among authors: young ep. J Immunother Cancer. 2023 Nov 24;11(11):e006985. doi: 10.1136/jitc-2023-006985. J Immunother Cancer. 2023. PMID: 38007238 Free PMC article.
Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach.
Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MV, Vanderboon EN, Hazard FK, Cho SJ, Avedian RS, Mohler DG, Zimel M, Wustrack R, Curtis C, Sirota M, Sweet-Cordero EA. Schott CR, et al. Among authors: young ep. Clin Cancer Res. 2024 Feb 16;30(4):849-864. doi: 10.1158/1078-0432.CCR-23-0873. Clin Cancer Res. 2024. PMID: 37703185 Free PMC article.
Discovery of VH domains that allosterically inhibit ENPP1.
Solomon PE, Bracken CJ, Carozza JA, Wang H, Young EP, Wellner A, Liu CC, Sweet-Cordero EA, Li L, Wells JA. Solomon PE, et al. Among authors: young ep. Nat Chem Biol. 2024 Jan;20(1):30-41. doi: 10.1038/s41589-023-01368-5. Epub 2023 Jul 3. Nat Chem Biol. 2024. PMID: 37400538 Free PMC article.
Development and characterization of new patient-derived xenograft (PDX) models of osteosarcoma with distinct metastatic capacities.
Schott CR, Koehne AL, Sayles LC, Young EP, Luck C, Yu K, Lee AG, Breese MR, Leung SG, Xu H, Shah AT, Liu HY, Spillinger A, Behroozfard IH, Marini KD, Dinh PT, Pons Ventura MAV, Vanderboon EN, Hazard FK, Cho SJ, Avedian RS, Mohler DG, Zimel M, Wustrack R, Curtis C, Sirota M, Sweet-Cordero EA. Schott CR, et al. Among authors: young ep. bioRxiv [Preprint]. 2023 Jan 20:2023.01.19.524562. doi: 10.1101/2023.01.19.524562. bioRxiv. 2023. PMID: 36711882 Free PMC article. Updated. Preprint.
Association of structural variation with cardiometabolic traits in Finns.
Chen L, Abel HJ, Das I, Larson DE, Ganel L, Kanchi KL, Regier AA, Young EP, Kang CJ, Scott AJ, Chiang C, Wang X, Lu S, Christ R, Service SK, Chiang CWK, Havulinna AS, Kuusisto J, Boehnke M, Laakso M, Palotie A, Ripatti S, Freimer NB, Locke AE, Stitziel NO, Hall IM. Chen L, et al. Among authors: young ep. Am J Hum Genet. 2021 Apr 1;108(4):583-596. doi: 10.1016/j.ajhg.2021.03.008. Am J Hum Genet. 2021. PMID: 33798444 Free PMC article.
SVEP1 is a human coronary artery disease locus that promotes atherosclerosis.
Jung IH, Elenbaas JS, Alisio A, Santana K, Young EP, Kang CJ, Kachroo P, Lavine KJ, Razani B, Mecham RP, Stitziel NO. Jung IH, et al. Among authors: young ep. Sci Transl Med. 2021 Mar 24;13(586):eabe0357. doi: 10.1126/scitranslmed.abe0357. Sci Transl Med. 2021. PMID: 33762433 Free PMC article.
NUP98-NSD1 Driven MDS/MPN in Childhood Masquerading as JMML.
Behnert A, Lee AG, Young EP, Breese MR, Leung SG, Behroozfard I, Maruffi M, Sweet-Cordero EA, Dvorak CC, Chu J, Stieglitz E. Behnert A, et al. Among authors: young ep. J Pediatr Hematol Oncol. 2021 Aug 1;43(6):e808-e811. doi: 10.1097/MPH.0000000000001913. J Pediatr Hematol Oncol. 2021. PMID: 32815876 Free PMC article.
73 results