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454 results

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Page 1
Four distinct trajectories of tau deposition identified in Alzheimer's disease.
Vogel JW, Young AL, Oxtoby NP, Smith R, Ossenkoppele R, Strandberg OT, La Joie R, Aksman LM, Grothe MJ, Iturria-Medina Y; Alzheimer’s Disease Neuroimaging Initiative; Pontecorvo MJ, Devous MD, Rabinovici GD, Alexander DC, Lyoo CH, Evans AC, Hansson O. Vogel JW, et al. Among authors: young al. Nat Med. 2021 May;27(5):871-881. doi: 10.1038/s41591-021-01309-6. Epub 2021 Apr 29. Nat Med. 2021. PMID: 33927414 Free PMC article.
A data-driven model of biomarker changes in sporadic Alzheimer's disease.
Young AL, Oxtoby NP, Daga P, Cash DM, Fox NC, Ourselin S, Schott JM, Alexander DC; Alzheimer’s Disease Neuroimaging Initiative. Young AL, et al. Brain. 2014 Sep;137(Pt 9):2564-77. doi: 10.1093/brain/awu176. Epub 2014 Jul 9. Brain. 2014. PMID: 25012224 Free PMC article.
Multiple Orderings of Events in Disease Progression.
Young AL, Oxtoby NP, Huang J, Marinescu RV, Daga P, Cash DM, Fox NC, Ourselin S, Schott JM, Alexander DC; Alzheimers Disease Neuroimaging Initiative. Young AL, et al. Inf Process Med Imaging. 2015;24:711-22. doi: 10.1007/978-3-319-19992-4_56. Inf Process Med Imaging. 2015. PMID: 26223048
A simulation system for biomarker evolution in neurodegenerative disease.
Young AL, Oxtoby NP, Ourselin S, Schott JM, Alexander DC; Alzheimer's Disease Neuroimaging Initiative. Young AL, et al. Med Image Anal. 2015 Dec;26(1):47-56. doi: 10.1016/j.media.2015.07.004. Epub 2015 Aug 15. Med Image Anal. 2015. PMID: 26356148 Free article.
An image-based model of brain volume biomarker changes in Huntington's disease.
Wijeratne PA, Young AL, Oxtoby NP, Marinescu RV, Firth NC, Johnson EB, Mohan A, Sampaio C, Scahill RI, Tabrizi SJ, Alexander DC. Wijeratne PA, et al. Among authors: young al. Ann Clin Transl Neurol. 2018 Apr 2;5(5):570-582. doi: 10.1002/acn3.558. eCollection 2018 May. Ann Clin Transl Neurol. 2018. PMID: 29761120 Free PMC article.
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.
Young AL, Marinescu RV, Oxtoby NP, Bocchetta M, Yong K, Firth NC, Cash DM, Thomas DL, Dick KM, Cardoso J, van Swieten J, Borroni B, Galimberti D, Masellis M, Tartaglia MC, Rowe JB, Graff C, Tagliavini F, Frisoni GB, Laforce R Jr, Finger E, de Mendonça A, Sorbi S, Warren JD, Crutch S, Fox NC, Ourselin S, Schott JM, Rohrer JD, Alexander DC; Genetic FTD Initiative (GENFI); Alzheimer’s Disease Neuroimaging Initiative (ADNI). Young AL, et al. Nat Commun. 2018 Oct 15;9(1):4273. doi: 10.1038/s41467-018-05892-0. Nat Commun. 2018. PMID: 30323170 Free PMC article.
Longitudinal neuroanatomical and cognitive progression of posterior cortical atrophy.
Firth NC, Primativo S, Marinescu RV, Shakespeare TJ, Suarez-Gonzalez A, Lehmann M, Carton A, Ocal D, Pavisic I, Paterson RW, Slattery CF, Foulkes AJM, Ridha BH, Gil-Néciga E, Oxtoby NP, Young AL, Modat M, Cardoso MJ, Ourselin S, Ryan NS, Miller BL, Rabinovici GD, Warrington EK, Rossor MN, Fox NC, Warren JD, Alexander DC, Schott JM, Yong KXX, Crutch SJ. Firth NC, et al. Among authors: young al. Brain. 2019 Jul 1;142(7):2082-2095. doi: 10.1093/brain/awz136. Brain. 2019. PMID: 31219516 Free PMC article.
Multi-study validation of data-driven disease progression models to characterize evolution of biomarkers in Alzheimer's disease.
Archetti D, Ingala S, Venkatraghavan V, Wottschel V, Young AL, Bellio M, Bron EE, Klein S, Barkhof F, Alexander DC, Oxtoby NP, Frisoni GB, Redolfi A; Alzheimer's Disease Neuroimaging Initiative; for EuroPOND Consortium. Archetti D, et al. Among authors: young al. Neuroimage Clin. 2019;24:101954. doi: 10.1016/j.nicl.2019.101954. Epub 2019 Jul 23. Neuroimage Clin. 2019. PMID: 31362149 Free PMC article.
454 results