You Q - Search Results

1

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3.

Mangoni AA, Tuccinardi T, Collina S, Vanden Eynde JJ, Muñoz-Torrero D, Karaman R, Siciliano C, de Sousa ME, Prokai-Tatrai K, Rautio J, Guillou C, Gütschow M, Galdiero S, Liu H, Agrofoglio LA, Sabatier JM, Hulme C, Kokotos G, You Q, Gomes PAC. Mangoni AA, et al. Among authors: you q. Molecules. 2018 Jun 30;23(7):1596. doi: 10.3390/molecules23071596. Molecules. 2018. PMID: 29966350 Free PMC article. No abstract available.

2

'Click Chemistry' Synthesis of Novel Natural Product-Like Caged Xanthones Bearing a 1,2,3-Triazole Moiety with Improved Druglike Properties as Orally Active Antitumor Agents.

Li X, Wu Y, Wang Y, You Q, Zhang X. Li X, et al. Among authors: you q. Molecules. 2017 Oct 27;22(11):1834. doi: 10.3390/molecules22111834. Molecules. 2017. PMID: 29077076 Free PMC article.

3

Forward or Backward: Lessons Learned from Small Molecule Drugs Approved by FDA from 2012 to 2022.

Gu M, Sun S, You Q, Wang L. Gu M, et al. Among authors: you q. Molecules. 2023 Dec 5;28(24):7941. doi: 10.3390/molecules28247941. Molecules. 2023. PMID: 38138431 Free PMC article. Review.

4

Lead Discovery of Type II BRAF V600E Inhibitors Targeting the Structurally Validated DFG-Out Conformation Based upon Selected Fragments.

Zhang Q, Zhang X, You Q. Zhang Q, et al. Among authors: you q. Molecules. 2016 Jul 16;21(7):879. doi: 10.3390/molecules21070879. Molecules. 2016. PMID: 27438814 Free PMC article.

5

Development of Novel Nrf2/ARE Inducers Bearing Pyrazino[2,1-a]isoquinolin Scaffold with Potent In Vitro Efficacy and Enhanced Physicochemical Properties.

Dai H, Jiao Q, Liu T, You Q, Jiang Z. Dai H, et al. Among authors: you q. Molecules. 2017 Sep 13;22(9):1541. doi: 10.3390/molecules22091541. Molecules. 2017. PMID: 28902165 Free PMC article.

6

Methods for the Discovery and Identification of Small Molecules Targeting Oxidative Stress-Related Protein-Protein Interactions: An Update.

Wu X, Zhang Q, Guo Y, Zhang H, Guo X, You Q, Wang L. Wu X, et al. Among authors: you q. Antioxidants (Basel). 2022 Mar 23;11(4):619. doi: 10.3390/antiox11040619. Antioxidants (Basel). 2022. PMID: 35453304 Free PMC article. Review.

7

Medicinal chemistry of metal chelating fragments in metalloenzyme active sites: A perspective.

Jiang Z, You Q, Zhang X. Jiang Z, et al. Among authors: you q. Eur J Med Chem. 2019 Mar 1;165:172-197. doi: 10.1016/j.ejmech.2019.01.018. Epub 2019 Jan 14. Eur J Med Chem. 2019. PMID: 30684796 Review.

8

Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective.

Zhang H, You QD, Xu XL. Zhang H, et al. J Med Chem. 2020 Apr 23;63(8):3785-3816. doi: 10.1021/acs.jmedchem.9b01039. Epub 2019 Dec 20. J Med Chem. 2020. PMID: 31820978 Review.

9

Targeting WD Repeat-Containing Protein 5 (WDR5): A Medicinal Chemistry Perspective.

Chen X, Xu J, Wang X, Long G, You Q, Guo X. Chen X, et al. Among authors: you q. J Med Chem. 2021 Aug 12;64(15):10537-10556. doi: 10.1021/acs.jmedchem.1c00037. Epub 2021 Jul 20. J Med Chem. 2021. PMID: 34283608 Review.

10

Hematopoietic Progenitor Kinase 1 in Tumor Immunology: A Medicinal Chemistry Perspective.

Zhu Q, Chen N, Tian X, Zhou Y, You Q, Xu X. Zhu Q, et al. Among authors: you q. J Med Chem. 2022 Jun 23;65(12):8065-8090. doi: 10.1021/acs.jmedchem.2c00172. Epub 2022 Jun 13. J Med Chem. 2022. PMID: 35696642 Review.

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