You J - Search Results

1

SARS-CoV-2 M^pro inhibitors with antiviral activity in a transgenic mouse model.

Qiao J, Li YS, Zeng R, Liu FL, Luo RH, Huang C, Wang YF, Zhang J, Quan B, Shen C, Mao X, Liu X, Sun W, Yang W, Ni X, Wang K, Xu L, Duan ZL, Zou QC, Zhang HL, Qu W, Long YH, Li MH, Yang RC, Liu X, You J, Zhou Y, Yao R, Li WP, Liu JM, Chen P, Liu Y, Lin GF, Yang X, Zou J, Li L, Hu Y, Lu GW, Li WM, Wei YQ, Zheng YT, Lei J, Yang S. Qiao J, et al. Among authors: you j. Science. 2021 Mar 26;371(6536):1374-1378. doi: 10.1126/science.abf1611. Epub 2021 Feb 18. Science. 2021. PMID: 33602867 Free PMC article.

2

Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model.

Yang W, Liu X, Song C, Ji S, Yang J, Liu Y, You J, Zhang J, Huang S, Cheng W, Shao Z, Li L, Yang S. Yang W, et al. Among authors: you j. Eur J Med Chem. 2021 Jan 1;209:112842. doi: 10.1016/j.ejmech.2020.112842. Epub 2020 Sep 18. Eur J Med Chem. 2021. PMID: 33065375

3

Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain.

Guo Y, Mao X, Xiong L, Xia A, You J, Lin G, Wu C, Huang L, Wang Y, Yang S. Guo Y, et al. Among authors: you j. Angew Chem Int Ed Engl. 2021 Apr 12;60(16):8760-8765. doi: 10.1002/anie.202017200. Epub 2021 Mar 8. Angew Chem Int Ed Engl. 2021. PMID: 33511756

4

Discovery of 2-vinyl-10H-phenothiazine derivatives as a class of ferroptosis inhibitors with minimal human Ether-a-go-go related gene (hERG) activity for the treatment of DOX-induced cardiomyopathy.

You J, Yang W, Ma R, Xia A, Zhang G, Fang Z, Guo N, Yang S, Li L. You J, et al. Bioorg Med Chem Lett. 2022 Oct 15;74:128911. doi: 10.1016/j.bmcl.2022.128911. Epub 2022 Jul 28. Bioorg Med Chem Lett. 2022. PMID: 35907606

5

Non-classical ferroptosis inhibition by a small molecule targeting PHB2.

Yang W, Mu B, You J, Tian C, Bin H, Xu Z, Zhang L, Ma R, Wu M, Zhang G, Huang C, Li L, Shao Z, Dai L, Désaubry L, Yang S. Yang W, et al. Among authors: you j. Nat Commun. 2022 Dec 3;13(1):7473. doi: 10.1038/s41467-022-35294-2. Nat Commun. 2022. PMID: 36463308 Free PMC article.

6

Discovery of 3-phenyl-1,2,4-oxadiazole derivatives as a new class of SARS-CoV-2 main protease inhibitors.

Guo N, Huang C, Qiao J, Li Y, Wang Y, Xia A, Zhang G, Fang Z, You J, Li L. Guo N, et al. Among authors: you j. Bioorg Med Chem Lett. 2023 Apr 15;86:129238. doi: 10.1016/j.bmcl.2023.129238. Epub 2023 Mar 15. Bioorg Med Chem Lett. 2023. PMID: 36924946 Free PMC article.

7

A new generation M^pro inhibitor with potent activity against SARS-CoV-2 Omicron variants.

Huang C, Shuai H, Qiao J, Hou Y, Zeng R, Xia A, Xie L, Fang Z, Li Y, Yoon C, Huang Q, Hu B, You J, Quan B, Zhao X, Guo N, Zhang S, Ma R, Zhang J, Wang Y, Yang R, Zhang S, Nan J, Xu H, Wang F, Lei J, Chu H, Yang S. Huang C, et al. Among authors: you j. Signal Transduct Target Ther. 2023 Mar 16;8(1):128. doi: 10.1038/s41392-023-01392-w. Signal Transduct Target Ther. 2023. PMID: 36928316 Free PMC article.

8

Discovery of 5-((1H-indazol-3-yl) methylene)-2-thioxoimidazolidin-4-one derivatives as a new class of AHR agonists with anti-psoriasis activity in a mouse model.

Zhang G, Xia Z, Tian C, Xia A, You J, Liu J, Yang S, Li L. Zhang G, et al. Among authors: you j. Bioorg Med Chem Lett. 2023 Aug 15;92:129383. doi: 10.1016/j.bmcl.2023.129383. Epub 2023 Jun 20. Bioorg Med Chem Lett. 2023. PMID: 37348572

9

The Operation Mode of Agricultural Supply Chain Finance Using Blockchain.

Wang Y, You J. Wang Y, et al. Among authors: you j. Comput Intell Neurosci. 2022 Sep 22;2022:3338030. doi: 10.1155/2022/3338030. eCollection 2022. Comput Intell Neurosci. 2022. PMID: 36188687 Free PMC article. Retracted.

10

Multifunctional gelatin nanoparticle stabilized-Pickering emulsion hydrogel based on dextran and amikacin with controlled drug release and enhanced antibacterial capability for promoting infected wound healing.

Zhang R, Huang X, Wu Q, Chu S, Bai X, Zhou Y, You J, Yang C, Tan H. Zhang R, et al. Among authors: you j. Int J Biol Macromol. 2024 Mar;262(Pt 2):130172. doi: 10.1016/j.ijbiomac.2024.130172. Epub 2024 Feb 13. Int J Biol Macromol. 2024. PMID: 38360230

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