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Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation.
Tokuyama T, Uosaki H, Sugiura A, Nishitai G, Takeda K, Nagashima S, Shiiba I, Ito N, Amo T, Mohri S, Nishimura A, Nishida M, Konno A, Hirai H, Ishido S, Yoshizawa T, Shindo T, Takada S, Kinugawa S, Inatome R, Yanagi S. Tokuyama T, et al. Among authors: yoshizawa t. iScience. 2022 Jun 11;25(7):104582. doi: 10.1016/j.isci.2022.104582. eCollection 2022 Jul 15. iScience. 2022. PMID: 35789860 Free PMC article.
Novel regulation of cardiac metabolism and homeostasis by the adrenomedullin-receptor activity-modifying protein 2 system.
Yoshizawa T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Iesato Y, Koyama T, Uetake R, Yang L, Yamauchi A, Tanaka M, Toriyama Y, Igarashi K, Nakada T, Kashihara T, Yamada M, Kawakami H, Nakanishi H, Taguchi R, Nakanishi T, Akazawa H, Shindo T. Yoshizawa T, et al. Hypertension. 2013 Feb;61(2):341-51. doi: 10.1161/HYPERTENSIONAHA.111.00647. Epub 2013 Jan 7. Hypertension. 2013. PMID: 23297372
Endogenous CGRP protects against neointimal hyperplasia following wire-induced vascular injury.
Yang L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yoshizawa T, Koyama T, Iesato Y, Uetake R, Yamauchi A, Tanaka M, Toriyama Y, Igarashi K, Shindo T. Yang L, et al. Among authors: yoshizawa t. J Mol Cell Cardiol. 2013 Jun;59:55-66. doi: 10.1016/j.yjmcc.2013.02.002. Epub 2013 Feb 15. J Mol Cell Cardiol. 2013. PMID: 23416515 Free article.
Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis.
Koyama T, Ochoa-Callejero L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Iinuma N, Arai T, Yoshizawa T, Iesato Y, Lei Y, Uetake R, Okimura A, Yamauchi A, Tanaka M, Igarashi K, Toriyama Y, Kawate H, Adams RH, Kawakami H, Mochizuki N, Martínez A, Shindo T. Koyama T, et al. Among authors: yoshizawa t. Circulation. 2013 Feb 19;127(7):842-53. doi: 10.1161/CIRCULATIONAHA.112.000756. Epub 2013 Jan 25. Circulation. 2013. PMID: 23355623 Free article.
Adrenomedullin-RAMP2 system is crucially involved in retinal angiogenesis.
Iesato Y, Toriyama Y, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yoshizawa T, Koyama T, Uetake R, Yang L, Yamauchi A, Tanaka M, Igarashi K, Murata T, Shindo T. Iesato Y, et al. Among authors: yoshizawa t. Am J Pathol. 2013 Jun;182(6):2380-90. doi: 10.1016/j.ajpath.2013.02.015. Epub 2013 Apr 4. Am J Pathol. 2013. PMID: 23562442 Free article.
Adrenomedullin-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection.
Uetake R, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Iesato Y, Yoshizawa T, Koyama T, Yang L, Toriyama Y, Yamauchi A, Igarashi K, Tanaka M, Kuwabara T, Mori K, Yanagita M, Mukoyama M, Shindo T. Uetake R, et al. Among authors: yoshizawa t. PLoS One. 2014 Feb 5;9(2):e87667. doi: 10.1371/journal.pone.0087667. eCollection 2014. PLoS One. 2014. PMID: 24505304 Free PMC article.
The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity.
Ichikawa-Shindo Y, Sakurai T, Kamiyoshi A, Kawate H, Iinuma N, Yoshizawa T, Koyama T, Fukuchi J, Iimuro S, Moriyama N, Kawakami H, Murata T, Kangawa K, Nagai R, Shindo T. Ichikawa-Shindo Y, et al. Among authors: yoshizawa t. J Clin Invest. 2008 Jan;118(1):29-39. doi: 10.1172/JCI33022. J Clin Invest. 2008. PMID: 18097473 Free PMC article.
891 results