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Functional characterization of single nucleotide polymorphisms with amino acid substitution in CYP1A2, CYP2A6, and CYP2B6 found in the Japanese population.
Iwasaki M, Yoshimura Y, Asahi S, Saito K, Sakai S, Morita S, Takenaka O, Inoda T, Kashiyama E, Aoyama A, Nakabayashi T, Omori S, Kuwabara T, Izumi T, Nakamura K, Takanaka K, Nakayama Y, Takeuchi M, Nakamura H, Kametani S, Terauchi Y, Hashizume T, Nagayama S, Kume T, Achira M, Kawai H, Kawashiro T, Nakamura A, Nakai Y, Kagayama A, Shiraga T, Niwa T, Yoshimura T, Morita J, Ohsawa F, Tani M, Osawa N, Ida K, Noguchi K. Iwasaki M, et al. Among authors: yoshimura y, yoshimura t. Drug Metab Pharmacokinet. 2004 Dec;19(6):444-52. doi: 10.2133/dmpk.19.444. Drug Metab Pharmacokinet. 2004. PMID: 15681899 Free article.
Autoinduction of MKC-963 [(R)-1-(1-cyclohexylethylamino)-4-phenylphthalazine] metabolism in healthy volunteers and its retrospective evaluation using primary human hepatocytes and cDNA-expressed enzymes.
Shimizu T, Akimoto K, Yoshimura T, Niwa T, Kobayashi K, Tsunoo M, Chiba K. Shimizu T, et al. Among authors: yoshimura t. Drug Metab Dispos. 2006 Jun;34(6):950-4. doi: 10.1124/dmd.105.007997. Epub 2006 Mar 10. Drug Metab Dispos. 2006. PMID: 16531475 Clinical Trial.
STR mutations on chromosome 15q cause thyrotropin resistance by activating a primate-specific enhancer of MIR7-2/MIR1179.
Grasberger H, Dumitrescu AM, Liao XH, Swanson EG, Weiss RE, Srichomkwun P, Pappa T, Chen J, Yoshimura T, Hoffmann P, França MM, Tagett R, Onigata K, Costagliola S, Ranchalis J, Vollger MR, Stergachis AB, Chong JX, Bamshad MJ, Smits G, Vassart G, Refetoff S. Grasberger H, et al. Among authors: yoshimura t. Nat Genet. 2024 May 7. doi: 10.1038/s41588-024-01717-7. Online ahead of print. Nat Genet. 2024. PMID: 38714869
IL-33 Reduces Saturated Fatty Acid Accumulation in Mouse Atherosclerotic Foci.
Hosomi Y, Okamura T, Sakai K, Yuge H, Yoshimura T, Majima S, Okada H, Senmaru T, Ushigome E, Nakanishi N, Satoh T, Akira S, Hamaguchi M, Fukui M. Hosomi Y, et al. Among authors: yoshimura t. Nutrients. 2024 Apr 17;16(8):1195. doi: 10.3390/nu16081195. Nutrients. 2024. PMID: 38674885 Free PMC article.
2,503 results