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S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
Sasaki M, Tabata K, Kishimoto M, Itakura Y, Kobayashi H, Ariizumi T, Uemura K, Toba S, Kusakabe S, Maruyama Y, Iida S, Nakajima N, Suzuki T, Yoshida S, Nobori H, Sanaki T, Kato T, Shishido T, Hall WW, Orba Y, Sato A, Sawa H. Sasaki M, et al. Among authors: yoshida s. Sci Transl Med. 2023 Jan 18;15(679):eabq4064. doi: 10.1126/scitranslmed.abq4064. Epub 2023 Jan 18. Sci Transl Med. 2023. PMID: 36327352 Free PMC article.
Efficacy comparison of 3CL protease inhibitors ensitrelvir and nirmatrelvir against SARS-CoV-2 in vitro and in vivo.
Kuroda T, Nobori H, Fukao K, Baba K, Matsumoto K, Yoshida S, Tanaka Y, Watari R, Oka R, Kasai Y, Inoue K, Kawashima S, Shimba A, Hayasaki-Kajiwara Y, Tanimura M, Zhang Q, Tachibana Y, Kato T, Shishido T. Kuroda T, et al. Among authors: yoshida s. J Antimicrob Chemother. 2023 Apr 3;78(4):946-952. doi: 10.1093/jac/dkad027. J Antimicrob Chemother. 2023. PMID: 36760083 Free PMC article.
Prophylactic effect of ensitrelvir in mice infected with SARS-CoV-2.
Nobori H, Baba K, Kuroda T, Baba K, Matsumoto K, Yoshida S, Watari R, Tachibana Y, Kato T, Fukao K. Nobori H, et al. Among authors: yoshida s. Antiviral Res. 2024 Apr;224:105852. doi: 10.1016/j.antiviral.2024.105852. Epub 2024 Feb 28. Antiviral Res. 2024. PMID: 38428748 Free article.
Cyclic Sesquiterpene-Flavanone [4+2] Hybrids, Syzygioblanes A-C, Found in an Indonesian Traditional Medicine, "Jampu Salo" (Syzygium oblanceolatum).
Koga N, Saito Y, Miyake K, Amuti S, Fukuyoshi S, Yoshida S, Sato S, Yamada Y, Ikeda A, Adachi N, Kawasaki M, Takasu A, Aramaki S, Senda T, Rahim A, Najib A, Alam G, Tanaka N, Nakagawa-Goto K. Koga N, et al. Among authors: yoshida s. Org Lett. 2024 May 10. doi: 10.1021/acs.orglett.4c01248. Online ahead of print. Org Lett. 2024. PMID: 38728049
7,893 results