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A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis.
Yoon SH, Meyer MB, Arevalo C, Tekguc M, Zhang C, Wang JS, Castro Andrade CD, Strauss K, Sato T, Benkusky NA, Lee SM, Berdeaux R, Foretz M, Sundberg TB, Xavier RJ, Adelmann CH, Brooks DJ, Anselmo A, Sadreyev RI, Rosales IA, Fisher DE, Gupta N, Morizane R, Greka A, Pike JW, Mannstadt M, Wein MN. Yoon SH, et al. J Clin Invest. 2023 May 1;133(9):e163627. doi: 10.1172/JCI163627. J Clin Invest. 2023. PMID: 36862513 Free PMC article.
Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption.
Tang CC, Castro Andrade CD, O'Meara MJ, Yoon SH, Sato T, Brooks DJ, Bouxsein ML, Martins JDS, Wang J, Gray NS, Misof B, Roschger P, Blouin S, Klaushofer K, Velduis-Vlug A, Vegting Y, Rosen CJ, O'Connell D, Sundberg TB, Xavier RJ, Ung P, Schlessinger A, Kronenberg HM, Berdeaux R, Foretz M, Wein MN. Tang CC, et al. Among authors: yoon sh. Elife. 2021 Jun 23;10:e67772. doi: 10.7554/eLife.67772. Elife. 2021. PMID: 34160349 Free PMC article.
Salt inducible kinases and PTH1R action.
Yoon SH, Tang CC, Wein MN. Yoon SH, et al. Vitam Horm. 2022;120:23-45. doi: 10.1016/bs.vh.2022.04.008. Epub 2022 Jul 11. Vitam Horm. 2022. PMID: 35953111
Structure-based design of selective, orally available salt-inducible kinase inhibitors that stimulate bone formation in mice.
Sato T, Andrade CDC, Yoon SH, Zhao Y, Greenlee WJ, Weber PC, Viswanathan U, Kulp J, Brooks DJ, Demay MB, Bouxsein ML, Mitlak B, Lanske B, Wein MN. Sato T, et al. Among authors: yoon sh. Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2214396119. doi: 10.1073/pnas.2214396119. Epub 2022 Dec 6. Proc Natl Acad Sci U S A. 2022. PMID: 36472957 Free PMC article.
Actions of Parathyroid Hormone Ligand Analogues in Humanized PTH1R Knockin Mice.
Daley EJ, Yoon SH, Reyes M, Bruce M, Brooks DJ, Bouxsein M, Potts JT, Kronenberg HM, Wein MN, Lanske B, Jüppner H, Gardella TJ. Daley EJ, et al. Among authors: yoon sh. Endocrinology. 2022 Jul 1;163(7):bqac054. doi: 10.1210/endocr/bqac054. Endocrinology. 2022. PMID: 35460406 Free PMC article.
1,834 results