Yoon M - Search Results

1

Using quantitative modeling tools to assess pharmacokinetic bias in epidemiological studies showing associations between biomarkers and health outcomes at low exposures.

Andersen ME, Mallick P, Clewell HJ 3rd, Yoon M, Olsen GW, Longnecker MP. Andersen ME, et al. Among authors: yoon m. Environ Res. 2021 Jun;197:111183. doi: 10.1016/j.envres.2021.111183. Epub 2021 Apr 20. Environ Res. 2021. PMID: 33887277 Free article. Review.

2

Lactational transfer of manganese in rats: predicting manganese tissue concentration in the dam and pups from inhalation exposure with a pharmacokinetic model.

Yoon M, Nong A, Clewell HJ 3rd, Taylor MD, Dorman DC, Andersen ME. Yoon M, et al. Toxicol Sci. 2009 Nov;112(1):23-43. doi: 10.1093/toxsci/kfp197. Epub 2009 Sep 2. Toxicol Sci. 2009. PMID: 19726576

3

Evaluating placental transfer and tissue concentrations of manganese in the pregnant rat and fetuses after inhalation exposures with a PBPK model.

Yoon M, Nong A, Clewell HJ 3rd, Taylor MD, Dorman DC, Andersen ME. Yoon M, et al. Toxicol Sci. 2009 Nov;112(1):44-58. doi: 10.1093/toxsci/kfp198. Epub 2009 Sep 2. Toxicol Sci. 2009. PMID: 19726578

4

Analysis of manganese tracer kinetics and target tissue dosimetry in monkeys and humans with multi-route physiologically based pharmacokinetic models.

Schroeter JD, Nong A, Yoon M, Taylor MD, Dorman DC, Andersen ME, Clewell HJ 3rd. Schroeter JD, et al. Among authors: yoon m. Toxicol Sci. 2011 Apr;120(2):481-98. doi: 10.1093/toxsci/kfq389. Epub 2010 Dec 27. Toxicol Sci. 2011. PMID: 21205636

5

Physiologically based pharmacokinetic modeling of fetal and neonatal manganese exposure in humans: describing manganese homeostasis during development.

Yoon M, Schroeter JD, Nong A, Taylor MD, Dorman DC, Andersen ME, Clewell HJ 3rd. Yoon M, et al. Toxicol Sci. 2011 Aug;122(2):297-316. doi: 10.1093/toxsci/kfr141. Epub 2011 May 27. Toxicol Sci. 2011. PMID: 21622944

6

A semiphysiologically based pharmacokinetic modeling approach to predict the dose-exposure relationship of an antiparasitic prodrug/active metabolite pair.

Yan GZ, Generaux CN, Yoon M, Goldsmith RB, Tidwell RR, Hall JE, Olson CA, Clewell HJ, Brouwer KL, Paine MF. Yan GZ, et al. Among authors: yoon m. Drug Metab Dispos. 2012 Jan;40(1):6-17. doi: 10.1124/dmd.111.040063. Epub 2011 Sep 27. Drug Metab Dispos. 2012. PMID: 21953913 Free PMC article. Clinical Trial.

7

Update on a Pharmacokinetic-Centric Alternative Tier II Program for MMT-Part II: Physiologically Based Pharmacokinetic Modeling and Manganese Risk Assessment.

Taylor MD, Clewell HJ 3rd, Andersen ME, Schroeter JD, Yoon M, Keene AM, Dorman DC. Taylor MD, et al. Among authors: yoon m. J Toxicol. 2012;2012:791431. doi: 10.1155/2012/791431. Epub 2012 May 7. J Toxicol. 2012. PMID: 22645610 Free PMC article.

8

Quantitative in vitro to in vivo extrapolation of cell-based toxicity assay results.

Yoon M, Campbell JL, Andersen ME, Clewell HJ. Yoon M, et al. Crit Rev Toxicol. 2012 Sep;42(8):633-52. doi: 10.3109/10408444.2012.692115. Epub 2012 Jun 6. Crit Rev Toxicol. 2012. PMID: 22667820 Review.

9

Application of a multi-route physiologically based pharmacokinetic model for manganese to evaluate dose-dependent neurological effects in monkeys.

Schroeter JD, Dorman DC, Yoon M, Nong A, Taylor MD, Andersen ME, Clewell HJ 3rd. Schroeter JD, et al. Among authors: yoon m. Toxicol Sci. 2012 Oct;129(2):432-46. doi: 10.1093/toxsci/kfs212. Epub 2012 Jun 21. Toxicol Sci. 2012. PMID: 22723044

10

Deriving an explicit hepatic clearance equation accounting for plasma protein binding and hepatocellular uptake.

Yoon M, Clewell HJ 3rd, Andersen ME. Yoon M, et al. Toxicol In Vitro. 2013 Feb;27(1):11-5. doi: 10.1016/j.tiv.2012.10.003. Epub 2012 Oct 17. Toxicol In Vitro. 2013. PMID: 23085432

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