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Neutral sphingomyelinase 2 is required for HIV-1 maturation.
Waheed AA, Zhu Y, Agostino E, Naing L, Hikichi Y, Soheilian F, Yoo SW, Song Y, Zhang P, Slusher BS, Haughey NJ, Freed EO. Waheed AA, et al. Among authors: yoo sw. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2219475120. doi: 10.1073/pnas.2219475120. Epub 2023 Jul 5. Proc Natl Acad Sci U S A. 2023. PMID: 37406093 Free PMC article.
Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties.
Figuera-Losada M, Stathis M, Dorskind JM, Thomas AG, Bandaru VV, Yoo SW, Westwood NJ, Rogers GW, McArthur JC, Haughey NJ, Slusher BS, Rojas C. Figuera-Losada M, et al. Among authors: yoo sw. PLoS One. 2015 May 26;10(5):e0124481. doi: 10.1371/journal.pone.0124481. eCollection 2015. PLoS One. 2015. PMID: 26010541 Free PMC article.
Inhibition of neutral sphingomyelinase 2 promotes remyelination.
Yoo SW, Agarwal A, Smith MD, Khuder SS, Baxi EG, Thomas AG, Rojas C, Moniruzzaman M, Slusher BS, Bergles DE, Calabresi PA, Haughey NJ. Yoo SW, et al. Sci Adv. 2020 Oct 2;6(40):eaba5210. doi: 10.1126/sciadv.aba5210. Print 2020 Oct. Sci Adv. 2020. PMID: 33008902 Free PMC article.
Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury.
Tallon C, Picciolini S, Yoo SW, Thomas AG, Pal A, Alt J, Carlomagno C, Gualerzi A, Rais R, Haughey NJ, Bedoni M, Slusher BS. Tallon C, et al. Among authors: yoo sw. Biochem Pharmacol. 2021 Dec;194:114796. doi: 10.1016/j.bcp.2021.114796. Epub 2021 Oct 20. Biochem Pharmacol. 2021. PMID: 34678224 Free PMC article.
DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.
Rojas C, Barnaeva E, Thomas AG, Hu X, Southall N, Marugan J, Chaudhuri AD, Yoo SW, Hin N, Stepanek O, Wu Y, Zimmermann SC, Gadiano AG, Tsukamoto T, Rais R, Haughey N, Ferrer M, Slusher BS. Rojas C, et al. Among authors: yoo sw. Sci Rep. 2018 Dec 7;8(1):17715. doi: 10.1038/s41598-018-36144-2. Sci Rep. 2018. PMID: 30531925 Free PMC article.
Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice.
Tallon C, Bell BJ, Sharma A, Pal A, Malvankar MM, Thomas AG, Yoo SW, Hollinger KR, Coleman K, Wilkinson EL, Kannan S, Haughey NJ, Kannan RM, Rais R, Slusher BS. Tallon C, et al. Among authors: yoo sw. Pharmaceutics. 2022 Sep 28;14(10):2066. doi: 10.3390/pharmaceutics14102066. Pharmaceutics. 2022. PMID: 36297501 Free PMC article.
194 results