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Rational prioritization strategy allows the design of macrolide derivatives that overcome antibiotic resistance.
König G, Sokkar P, Pryk N, Heinrich S, Möller D, Cimicata G, Matzov D, Dietze P, Thiel W, Bashan A, Bandow JE, Zuegg J, Yonath A, Schulz F, Sanchez-Garcia E. König G, et al. Among authors: yonath a. Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2113632118. doi: 10.1073/pnas.2113632118. Proc Natl Acad Sci U S A. 2021. PMID: 34750269 Free PMC article.
Structural basis for cross-resistance to ribosomal PTC antibiotics.
Davidovich C, Bashan A, Yonath A. Davidovich C, et al. Among authors: yonath a. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20665-70. doi: 10.1073/pnas.0810826105. Epub 2008 Dec 19. Proc Natl Acad Sci U S A. 2008. PMID: 19098107 Free PMC article.
The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics.
Auerbach T, Mermershtain I, Davidovich C, Bashan A, Belousoff M, Wekselman I, Zimmerman E, Xiong L, Klepacki D, Arakawa K, Kinashi H, Mankin AS, Yonath A. Auerbach T, et al. Among authors: yonath a. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1983-8. doi: 10.1073/pnas.0914100107. Epub 2010 Jan 11. Proc Natl Acad Sci U S A. 2010. PMID: 20080686 Free PMC article.
A Bright Future for Antibiotics?
Matzov D, Bashan A, Yonath A. Matzov D, et al. Among authors: yonath a. Annu Rev Biochem. 2017 Jun 20;86:567-583. doi: 10.1146/annurev-biochem-061516-044617. Annu Rev Biochem. 2017. PMID: 28654325 Review.
Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate.
Halfon Y, Jimenez-Fernandez A, La Rosa R, Espinosa Portero R, Krogh Johansen H, Matzov D, Eyal Z, Bashan A, Zimmerman E, Belousoff M, Molin S, Yonath A. Halfon Y, et al. Among authors: yonath a. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22275-22281. doi: 10.1073/pnas.1909831116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611393 Free PMC article.
151 results