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BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin state.
Xiao M, Kondo S, Nomura M, Kato S, Nishimura K, Zang W, Zhang Y, Akashi T, Viny A, Shigehiro T, Ikawa T, Yamazaki H, Fukumoto M, Tanaka A, Hayashi Y, Koike Y, Aoyama Y, Ito H, Nishikawa H, Kitamura T, Kanai A, Yokoyama A, Fujiwara T, Goyama S, Noguchi H, Lee SC, Toyoda A, Hinohara K, Abdel-Wahab O, Inoue D. Xiao M, et al. Among authors: yokoyama a. Nat Commun. 2023 Dec 15;14(1):8372. doi: 10.1038/s41467-023-44081-6. Nat Commun. 2023. PMID: 38102116 Free PMC article.
Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia.
Kadono M, Kanai A, Nagamachi A, Shinriki S, Kawata J, Iwato K, Kyo T, Oshima K, Yokoyama A, Kawamura T, Nagase R, Inoue D, Kitamura T, Inaba T, Ichinohe T, Matsui H. Kadono M, et al. Among authors: yokoyama a. Exp Hematol. 2016 Aug;44(8):745-754.e4. doi: 10.1016/j.exphem.2016.04.017. Epub 2016 May 9. Exp Hematol. 2016. PMID: 27174803 Free article.
A novel ASXL1-OGT axis plays roles in H3K4 methylation and tumor suppression in myeloid malignancies.
Inoue D, Fujino T, Sheridan P, Zhang YZ, Nagase R, Horikawa S, Li Z, Matsui H, Kanai A, Saika M, Yamaguchi R, Kozuka-Hata H, Kawabata KC, Yokoyama A, Goyama S, Inaba T, Imoto S, Miyano S, Xu M, Yang FC, Oyama M, Kitamura T. Inoue D, et al. Among authors: yokoyama a. Leukemia. 2018 Jun;32(6):1327-1337. doi: 10.1038/s41375-018-0083-3. Epub 2018 Mar 3. Leukemia. 2018. PMID: 29556021
Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis.
Asada S, Goyama S, Inoue D, Shikata S, Takeda R, Fukushima T, Yonezawa T, Fujino T, Hayashi Y, Kawabata KC, Fukuyama T, Tanaka Y, Yokoyama A, Yamazaki S, Kozuka-Hata H, Oyama M, Kojima S, Kawazu M, Mano H, Kitamura T. Asada S, et al. Among authors: yokoyama a. Nat Commun. 2018 Jul 16;9(1):2733. doi: 10.1038/s41467-018-05085-9. Nat Commun. 2018. PMID: 30013160 Free PMC article.
HHEX promotes myeloid transformation in cooperation with mutant ASXL1.
Takeda R, Asada S, Park SJ, Yokoyama A, Becker HJ, Kanai A, Visconte V, Hershberger C, Hayashi Y, Yonezawa T, Tamura M, Fukushima T, Tanaka Y, Fukuyama T, Matsumoto A, Yamasaki S, Nakai K, Yamazaki S, Inaba T, Shibata T, Inoue D, Honda H, Goyama S, Maciejewski JP, Kitamura T. Takeda R, et al. Among authors: yokoyama a. Blood. 2020 Oct 1;136(14):1670-1684. doi: 10.1182/blood.2019004613. Blood. 2020. PMID: 32492700 Free article.
1,463 results