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Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion.
Tang N, Matsuzaka T, Suzuki M, Nakano Y, Zao H, Yokoo T, Suzuki-Kemuriyama N, Kuba M, Okajima Y, Takeuchi Y, Kobayashi K, Iwasaki H, Yatoh S, Takahashi A, Suzuki H, Sone H, Shimada M, Nakagawa Y, Yahagi N, Yamada N, Shimano H. Tang N, et al. Among authors: yokoo t. Biochem Biophys Res Commun. 2014 Jul 18;450(1):318-23. doi: 10.1016/j.bbrc.2014.05.113. Epub 2014 Jun 2. Biochem Biophys Res Commun. 2014. PMID: 24938128
Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity.
Zhao H, Matsuzaka T, Nakano Y, Motomura K, Tang N, Yokoo T, Okajima Y, Han SI, Takeuchi Y, Aita Y, Iwasaki H, Yatoh S, Suzuki H, Sekiya M, Yahagi N, Nakagawa Y, Sone H, Yamada N, Shimano H. Zhao H, et al. Among authors: yokoo t. Diabetes. 2017 Jul;66(7):1833-1846. doi: 10.2337/db16-1277. Epub 2017 May 1. Diabetes. 2017. PMID: 28461456
Statins downregulate ATP-binding-cassette transporter A1 gene expression in macrophages.
Sone H, Shimano H, Shu M, Nakakuki M, Takahashi A, Sakai M, Sakamoto Y, Yokoo T, Matsuzaka K, Okazaki H, Nakagawa Y, Iida KT, Suzuki H, Toyoshima H, Horiuchi S, Yamada N. Sone H, et al. Among authors: yokoo t. Biochem Biophys Res Commun. 2004 Apr 9;316(3):790-4. doi: 10.1016/j.bbrc.2004.02.121. Biochem Biophys Res Commun. 2004. PMID: 15033469
WGEF is a novel RhoGEF expressed in intestine, liver, heart, and kidney.
Wang Y, Suzuki H, Yokoo T, Tada-Iida K, Kihara R, Miura M, Watanabe K, Sone H, Shimano H, Toyoshima H, Yamada N. Wang Y, et al. Among authors: yokoo t. Biochem Biophys Res Commun. 2004 Nov 19;324(3):1053-8. doi: 10.1016/j.bbrc.2004.09.153. Biochem Biophys Res Commun. 2004. PMID: 15485661
Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice.
Kato T, Shimano H, Yamamoto T, Yokoo T, Endo Y, Ishikawa M, Matsuzaka T, Nakagawa Y, Kumadaki S, Yahagi N, Takahashi A, Sone H, Suzuki H, Toyoshima H, Hasty AH, Takahashi S, Gomi H, Izumi T, Yamada N. Kato T, et al. Among authors: yokoo t. Cell Metab. 2006 Aug;4(2):143-54. doi: 10.1016/j.cmet.2006.06.009. Cell Metab. 2006. PMID: 16890542 Free article.
Acetyl-coenzyme A synthetase is a lipogenic enzyme controlled by SREBP-1 and energy status.
Sone H, Shimano H, Sakakura Y, Inoue N, Amemiya-Kudo M, Yahagi N, Osawa M, Suzuki H, Yokoo T, Takahashi A, Iida K, Toyoshima H, Iwama A, Yamada N. Sone H, et al. Among authors: yokoo t. Am J Physiol Endocrinol Metab. 2002 Jan;282(1):E222-30. doi: 10.1152/ajpendo.00189.2001. Am J Physiol Endocrinol Metab. 2002. PMID: 11739104 Free article.
632 results