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Ursolic Acid Inhibits Na+/K+-ATPase Activity and Prevents TNF-α-Induced Gene Expression by Blocking Amino Acid Transport and Cellular Protein Synthesis.
Biomolecules. 2011 Nov 7;1(1):32-47. doi: 10.3390/biom1010032.
Biomolecules. 2011.
PMID: 24970122
Free PMC article.
Ursolic acid, a natural pentacyclic triterpenoid, inhibits intracellular trafficking of proteins and induces accumulation of intercellular adhesion molecule-1 linked to high-mannose-type glycans in the endoplasmic reticulum.
Mitsuda S, Yokomichi T, Yokoigawa J, Kataoka T.
Mitsuda S, et al. Among authors: yokomichi t.
FEBS Open Bio. 2014 Feb 22;4:229-39. doi: 10.1016/j.fob.2014.02.009. eCollection 2014.
FEBS Open Bio. 2014.
PMID: 24649404
Free PMC article.
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Cardenolide aglycones inhibit tumor necrosis factor α-induced expression of intercellular adhesion molecule-1 at the translation step by blocking Na⁺/K⁺-ATPase.
Okina Y, Takeuchi F, Yokomichi T, Takada Y, Kataoka T.
Okina Y, et al. Among authors: yokomichi t.
Biol Pharm Bull. 2015;38(1):39-47. doi: 10.1248/bpb.b14-00532.
Biol Pharm Bull. 2015.
PMID: 25744456
Free article.
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Betulinic acid and oleanolic acid, natural pentacyclic triterpenoids, interfere with N-linked glycan modifications to intercellular adhesion molecule-1, but not its intracellular transport to the cell surface.
Hiramatsu R, Fukuhara S, Mitsuda S, Yokomichi T, Kataoka T.
Hiramatsu R, et al. Among authors: yokomichi t.
Eur J Pharmacol. 2015 Nov 15;767:126-34. doi: 10.1016/j.ejphar.2015.10.017. Epub 2015 Oct 14.
Eur J Pharmacol. 2015.
PMID: 26460147
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