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Transcriptome-wide In Vitro Effects of Aspirin on Patient-derived Normal Colon Organoids.
Devall MAM, Drew DA, Dampier CH, Plummer SJ, Eaton S, Bryant J, Díez-Obrero V, Mo J, Kedrin D, Zerjav DC, Takacsi-Nagy O, Jennelle LT, Ali MW, Yilmaz ÖH, Moreno V, Powell SM, Chan AT, Peters U, Casey G. Devall MAM, et al. Among authors: yilmaz oh. Cancer Prev Res (Phila). 2021 Dec;14(12):1089-1100. doi: 10.1158/1940-6207.CAPR-21-0041. Epub 2021 Aug 13. Cancer Prev Res (Phila). 2021. PMID: 34389629 Free PMC article.
Colorectal cancer models for novel drug discovery.
Golovko D, Kedrin D, Yilmaz ÖH, Roper J. Golovko D, et al. Among authors: yilmaz oh. Expert Opin Drug Discov. 2015;10(11):1217-29. doi: 10.1517/17460441.2015.1079618. Epub 2015 Aug 21. Expert Opin Drug Discov. 2015. PMID: 26295972 Free PMC article. Review.
In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera FJ, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. Roper J, et al. Among authors: yilmaz oh. Nat Biotechnol. 2017 Jun;35(6):569-576. doi: 10.1038/nbt.3836. Epub 2017 May 1. Nat Biotechnol. 2017. PMID: 28459449 Free PMC article.
Germline Determinants of Esophageal Adenocarcinoma.
Lee M, Eng G, Handte-Reinecker A; MGH-MIT Gastrointestinal Cohorts Working Group; Deshpande VS, Yilmaz OH, Gala MK. Lee M, et al. Among authors: yilmaz oh. Gastroenterology. 2023 Nov;165(5):1276-1279.e7. doi: 10.1053/j.gastro.2023.07.015. Epub 2023 Jul 26. Gastroenterology. 2023. PMID: 37507074 Free PMC article. No abstract available.
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, Lamming DW, Dogum R, Guo G, Bell GW, Selig M, Nielsen GP, Gupta N, Ferrone CR, Deshpande V, Yuan GC, Orkin SH, Sabatini DM, Yilmaz ÖH. Beyaz S, et al. Among authors: yilmaz oh. Nature. 2016 Mar 3;531(7592):53-8. doi: 10.1038/nature17173. Nature. 2016. PMID: 26935695 Free PMC article.
PKM2 is not required for colon cancer initiated by APC loss.
Lau AN, Israelsen WJ, Roper J, Sinnamon MJ, Georgeon L, Dayton TL, Hillis AL, Yilmaz OH, Di Vizio D, Hung KE, Vander Heiden MG. Lau AN, et al. Among authors: yilmaz oh. Cancer Metab. 2017 Nov 30;5:10. doi: 10.1186/s40170-017-0172-1. eCollection 2017. Cancer Metab. 2017. PMID: 29214019 Free PMC article.
From 3D Organoids back to 2D Enteroids.
Braverman J, Yilmaz ÖH. Braverman J, et al. Among authors: yilmaz oh. Dev Cell. 2018 Mar 12;44(5):533-534. doi: 10.1016/j.devcel.2018.02.016. Dev Cell. 2018. PMID: 29533766 Free article.
Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.
Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, Kobayashi H, Putoczki TL, Hayakawa Y, Leedham SJ, Abud HE, Yilmaz ÖH, Marker J, Klebe S, Wirapati P, Mukherjee S, Tejpar S, Leggett BA, Whitehall VLJ, Worthley DL, Woods SL. Lannagan TRM, et al. Among authors: yilmaz oh. Gut. 2019 Apr;68(4):684-692. doi: 10.1136/gutjnl-2017-315920. Epub 2018 Apr 17. Gut. 2019. PMID: 29666172 Free PMC article.
158 results