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RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD.
Van Eeckhoutte HP, Donovan C, Kim RY, Conlon TM, Ansari M, Khan H, Jayaraman R, Hansbro NG, Dondelinger Y, Delanghe T, Beal AM, Geddes B, Bertin J, Vanden Berghe T, De Volder J, Maes T, Vandenabeele P, Vanaudenaerde BM, Deforce D, Škevin S, Van Nieuwerburgh F, Verhamme FM, Joos GF, Idrees S, Schiller HB, Yildirim AÖ, Faiz A, Bertrand MJM, Brusselle GG, Hansbro PM, Bracke KR. Van Eeckhoutte HP, et al. Among authors: yildirim ao. Eur Respir J. 2023 Apr 1;61(4):2201506. doi: 10.1183/13993003.01506-2022. Print 2023 Apr. Eur Respir J. 2023. PMID: 36549711
Activation of the WNT/β-catenin pathway attenuates experimental emphysema.
Kneidinger N, Yildirim AÖ, Callegari J, Takenaka S, Stein MM, Dumitrascu R, Bohla A, Bracke KR, Morty RE, Brusselle GG, Schermuly RT, Eickelberg O, Königshoff M. Kneidinger N, et al. Among authors: yildirim ao. Am J Respir Crit Care Med. 2011 Mar 15;183(6):723-33. doi: 10.1164/rccm.200910-1560OC. Epub 2010 Oct 1. Am J Respir Crit Care Med. 2011. PMID: 20889911
Inflammaging increases susceptibility to cigarette smoke-induced COPD.
John-Schuster G, Günter S, Hager K, Conlon TM, Eickelberg O, Yildirim AÖ. John-Schuster G, et al. Among authors: yildirim ao. Oncotarget. 2016 May 24;7(21):30068-83. doi: 10.18632/oncotarget.4027. Oncotarget. 2016. PMID: 26284585 Free PMC article.
Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice.
Jia J, Conlon TM, Ballester Lopez C, Seimetz M, Bednorz M, Zhou-Suckow Z, Weissmann N, Eickelberg O, Mall MA, Yildirim AÖ. Jia J, et al. Among authors: yildirim ao. Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L602-10. doi: 10.1152/ajplung.00124.2016. Epub 2016 Jul 22. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27448665 Free article.
Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease.
Jia J, Conlon TM, Sarker RS, Taşdemir D, Smirnova NF, Srivastava B, Verleden SE, Güneş G, Wu X, Prehn C, Gao J, Heinzelmann K, Lintelmann J, Irmler M, Pfeiffer S, Schloter M, Zimmermann R, Hrabé de Angelis M, Beckers J, Adamski J, Bayram H, Eickelberg O, Yildirim AÖ. Jia J, et al. Among authors: yildirim ao. EMBO Mol Med. 2018 May;10(5):e8349. doi: 10.15252/emmm.201708349. EMBO Mol Med. 2018. PMID: 29674392 Free PMC article.
CARM1 regulates senescence during airway epithelial cell injury in COPD pathogenesis.
Sarker RSJ, Conlon TM, Morrone C, Srivastava B, Konyalilar N, Verleden SE, Bayram H, Fehrenbach H, Yildirim AÖ. Sarker RSJ, et al. Among authors: yildirim ao. Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L602-L614. doi: 10.1152/ajplung.00441.2018. Epub 2019 Aug 28. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31461302 Free article.
209 results